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Erina Yatmasari
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INDONESIA
Oceana Biomedicina Journal
Published by Universitas Hang Tuah
ISSN : -     EISSN : 26140519     DOI : https://doi.org/10.30649/obj
Core Subject : Health,
Dentistry Health Professions Medicine & Pharmacology Nursing Public Health
Oceana Biomedicina Journal is an open access journal of health and medicine. Specifically, the journal focuses on marine medicine, hyperbaric medicine and health, medicine on ships, harbor health, maritime and coastal health, medicolegal studies related to ships, ports and districts, maritime/coastal communities and fishermen, epidemiological aspects of diseases, disabilities and disorders that occur on ships and affect boat workers, ports and maritime zones, coastal areas, fishermen communities and their families, including pharmacological and non-pharmacological prevention and treatment management policies; and miscellanous.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 51 Documents
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A VARIASI KOSENTRASI EKSTRAK ETANOL KULIT BUAH MANGGA HARUM MANIS (Mangifera indica L var. arum manis) TERHADAP FORMULA SEDIAAN GEL HAND SANITIZER SEBAGAI ANTIBAKTERI Yuska Noviyanti; Hepiyansori Hepiyansori; Tamara Dwi Insani
Denta Journal Kedokteran Gigi Vol 4 No 2 (2021): Oceana Biomedicina Journal Volume 4 Issue (No) 2
Publisher : Universitas Hang Tuah

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Abstract

One of the medicinal plants that can be used as a source of natural medicine is mango (Mangifera indica L.) because it contains secondary metabolite compounds, mango plants contain many benefits both at the root, skin, leaves, fruits and seeds. Mango skin contains important active compounds such as phenolic compounds, carotenoids, flavonoids and anthocyanins. Sweet Arum mango skin has antibacterial activity. The extraction method used is maceration with 96% ethanol solvent. The formulation was prepared using Na.CMC as a gelling agent with a concentration of 2%, 4%, 8%. The evaluation test of mango skin extract hand sanitazer preparation includes organoleptic test, homogeneity test, pH test, spreadability test, sticking test, irritation test and antibacterial test. The results showed that the physical properties of the gel preparations had an influence on the physical properties of the mango skin extract gel (Mangifera indica L). Based on the antibacterial activity test the concentration of 2%, 4%, 8% which most strongly shows the antibacterial activity at a concentration of 8% with an average value of 18.28 mm.    
Effects of Morning’s Prayer Routines in The Congregation on Random Blood Sugar Levels of Elderly at Al Wahyu Mosque Rungkut Surabaya Indri Ngesti Rahayu; Lani Diana; R. Varidianto Yudo Tjahjono
Denta Journal Kedokteran Gigi Vol 4 No 2 (2021): Oceana Biomedicina Journal Volume 4 Issue (No) 2
Publisher : Universitas Hang Tuah

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Background: Increased health problems in the elderly occur because of the aging process that causes many changes in their body. One of the changes istheincrease in blood glucose more than normal and at risk of diabetes mellitus. Morning prayer can be a religious coping and regular physical activity that lowers blood sugar levels. Objective: to analyze the effect of the morning prayer routines in the congregation on random blood sugar levels of the elderly at Al-Wahyu Mosque Rungkut Surabaya. Method:This study was an observational analytic study with a cross-sectional design using 30 respondents. The group studied was the congregation of the morning prayers of the Al Wahyu MosqueRungkut Surabaya which was over 45-year-old which undergoes random blood sugar levels measurement. Results:The Independent t-testmethodshowedthat the value of signification was 0,000 (p<0,05) which means that there is the influence of the morning prayer’s routines in the congregation on random blood sugar levels of the elderly at Al-Wahyu Mosque Rungkut Surabaya. Conclusion:Elderly people who routinely carry out the morning prayer routines in the congregation have lower blood sugar levels than elderly people who are not routine.
UJI POTENSI ANTI KANKER EKTRAK ETANOL BIJI KEBIUL (Caesalpinia bonduc (L) Roxb) DENGAN METODE BRINE SHRIMP LETHALITY TEST (BSLT) Densi Selpia Sopianti; Aina Fathkil; Yesa Christine Sanuki
Denta Journal Kedokteran Gigi Vol 4 No 2 (2021): Oceana Biomedicina Journal Volume 4 Issue (No) 2
Publisher : Universitas Hang Tuah

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Cancer becomes a global health problem which is estimated to continue to increase in number. The prevalence of cancer in Indonesia is 1.4% or around 347,792 people. Cancer treatment is currently carried out with chemotherapy, radiotherapy, and surgery. At present many active compounds from herbal plants are believed to be one of the alternatives used by the community as an anticancer, shown by several studies and the availability of active compounds from a single herbal plant isolated from plants as anticancer easily found by the community and have minimal side effects. One of the potential plants in Bengkulu is Kebiul (Caesalpiniabonduc (L.) Roxb) which, according to the Bengkulu community, is used for various diseases. The purpose of this study is that the researchers wanted to test the potential of the active compound of whistle seeds (Caesalpiniabonduc (L.) Roxb) with the Brine Shrimp Lethality Test method. The stages of this research were by making dried simplicia from whistle seeds then extracted with 96% ethanol and evaporated on a rotary evaporator until thick ethanol extract was obtained. The extract was tested using the BSLT Method, calculated the number of larval deaths and measured LD50. The results of the probit value equation analysis showed the LC50 value of the ethanol extract of whistle seeds was 11,1943μg/mL, this shows that the ethanol extract of the whistle seeds was very toxic which was indicated by LC50 values ​​<30 μg / mL.
AKTIVITAS ANTIBAKTERI EKSTRAK KAYU SIWAK (Salvadora persica) TERHADAP BAKTERI Staphylococcus epidermidis Nugroho Eko W B
Denta Journal Kedokteran Gigi Vol 4 No 2 (2021): Oceana Biomedicina Journal Volume 4 Issue (No) 2
Publisher : Universitas Hang Tuah

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Background:Siwak is a plant that grows in the Arabian Peninsula which is used to clean teeth. Siwak has antibacterial properties because it contains flavonoids and alkaloids. This study aims to prove whether the extract of siwak stem powder can be used to inhibit the growth of Staphylococcus epidermidis bacteria Methods: In this study, using the Only Post Test Control Group Design method, namely pure experimental treatment and measuring the dependent variable. This study used 24 samples which were divided into four replications and six treatments. The study used extracts of siwak stems at concentrations of 25%, 50%, 75% and 100% and used clindamycin as a positive control and aquadest as a negative control. Research Results: The results showed that the average inhibition zones of siwak stem extract on the growth of Staphylococcus epidermidis from concentrations of 25%, 50%, 75%, and 100% were 0 mm, 0 mm, 10.01 mm and 14.65 mm. Conclusion: At a concentration of 75% ethanol extract of siwak stems, it was able to exert an inhibitory effect on the growth of Staphylococcus epidermidis bacteria but was still unable to match the inhibitory power of clindamycin.
KEGAWATAN PADA REAKSI TRANSFUSI Hendrata Erry Andisari
Denta Journal Kedokteran Gigi Vol 4 No 2 (2021): Oceana Biomedicina Journal Volume 4 Issue (No) 2
Publisher : Universitas Hang Tuah

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Reaksi tranfusi dapat dibedakan antara yang dimediasi imun dan tidak dimediasi imun. Keduanya dapat terjadi segera maupun reaksinya bisa lambat. Reaksi tranfusi yang dimediasi imun biasanya terjadi akibat aloantibodi setelah terekspose dengan antigen asing seperti kehamilan, tranfusi atau transplantasi. Kontaminan leukosit dapat menyebabkan aloimmunisasi, transmisi dari penyakit menular, TRALI dan imunomodulasi. Dengan pelatihan yang tepat untuk mengenali tanda dan gejala reaksi transfusi, komplikasi yang muncul akibat transfusi dapat dihindari. Diketahuinya penyebab sebagian besar reaksi transfusi bersifat klerikal sehingga dilakukan usaha untuk mencegah kesalahan klerikal sepanjang proses transfusi. Eksklusi kontaminan leukosit dari darah dan produk darah dapat mengurangi insiden FNHTR, aloimunisasi, dan imunosupresi. Filtrasi darah dan produk darah sebelum penyimpanan dapat menjadi cara yang efektif untuk mengatasi masalah tersebut terkait kontaminasi leukosit. Jika protokol transfusi yang tepat serta prosedur operasional standar diikuti, maka insiden reaksi transfusi dapat sangat menurun.
MIKROPENIS PADA ANAK DENGAN BERAT BADAN NORMAL Peter Gunawan Tandean
Denta Journal Kedokteran Gigi Vol 4 No 2 (2021): Oceana Biomedicina Journal Volume 4 Issue (No) 2
Publisher : Universitas Hang Tuah

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Latar Belakang: Mikropenis adalah diagnosis medis yang seringkali salah untuk ditegakkan. Mikropenis dapat terjadi sebagai kelainan tunggal dengan sendirinya maupun sebagai salah satu gejala dari suatu penyakit. Tujuan: Laporan kasus ini diperlukan untuk menegakkan diagnosis penyebab mikropenis pada anak laki-laki dengan berat badan normal. Metode: Metode yang digunakan adalah dengan melakukan penegakkan diagnosis secara lege artists berdasarkan referensi ilmiah mutakhir. Hasil: Laporan kasus ini memberikan hasil mengenai penegakkan diagnosis penyebab mikropenis pada anak laki-laki dengan berat badan normal. Kesimpulan: Kesimpulan dari laporan kasus ini adalah didapatkannya penyebab dari mikropenis dari anak laki-laki dengan berat badan normal.
EFEKTIVITAS ANTIVIRUS CORONA BERBASIS EUCALYPTUS DI INDONESIA Imamul Choir AM
Denta Journal Kedokteran Gigi Vol 4 No 2 (2021): Oceana Biomedicina Journal Volume 4 Issue (No) 2
Publisher : Universitas Hang Tuah

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COVID-19 adalah penyakit yang disebabkan oleh Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) dan menyerang pada sistem pernapasan. Gejala awal dari penyakit ini antara lain batuk, demam, nyeri pada tenggorokan, sakit kepala, hilangnya indra perasa dan penciuman. COVID-19 (Corona Virus Disease 2019) pertama kali ditemukan di Wuhan, China pada akhir Desember 2019. Epidemi menyebar dengan cepat diseluruh dunia dalam 3 bulan dan dicirikan sebagai pandemi oleh WHO. Hingga saat ini vaksin masih melalui tahap uji dan masih belum berhasil. Beberapa upaya pembuatan antivirus untuk COVID-19 telah dilakukan Kementerian Pertanian di Indonesia. Diantaranya dengan menggunakan tanaman eucalyptus yang memiliki potensi ampuh melawan virus. Minyak atsiri eucalyptus memiliki senyawa 1,8-cineole (eucalyptol) yang merupakan komponen utama dari minyak atsiri dan ditemukan dalam daun eucalyptus dan Senyawa ini memiliki aktivitas antivirus, anti-inflamasi, dan antimikroba. Senyawa eucalyptol dapat berfungsi menghambat replikasi coronavirus dengan mengikat protein Mpro yang terdapat pada virus. Protein tersebut berperan dalam pematangan virus dan pembelahan polyprotein virus sehingga dapat mencegah penyebaran infeksi.
Extended Spectrum Beta-Lactamase (ESBL) Verna Biutifasari
Denta Journal Kedokteran Gigi Vol 1 No 1 (2018): Oceana Biomedicina Journal Vol 1 Issue (No) 1 January-June 2018
Publisher : Universitas Hang Tuah

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Antibiotics have been widely used today. Use of antibiotics is also often used in mass and not in accordance with the indication, among others, in a particular case of fish poisoning on the beach, often the treatment is given antibiotics without clearlyindication. Use of antibiotics are excessive and not in accordance with the clinical, can cause resistance to these antibioticsOne of the antibiotics used is a beta-lactam antibiotic, that works inhibits cell walls. The inappropriate use of beta-lactam antibiotics can lead to resistance to these antibiotics. Resistance to beta-lactam can occur at various levels. One of the resistances can occur is resistance to Extended Spectrum Broad Lactamase (ESBL)Extended spectrum beta-lactamase is an enzyme that has the ability to hydrolyze penicillin-type antibiotics, first-generation cephalosporins, two, and three as well as monobactam groups and cause resistance throughout the antibiotic.ESBL is produced by many Enterobactericeae (especially Escherichia coli) and Klebsiella pneumoniae. Enterobacteriaceae has 3 resistance patterns caused by broadspectrum beta-lactamase, beta-lactamase-resistant inhibitors (TEM derivatives), excessive cephalosporinase. ESBL can be difficult to detect because ESBL has differentiatedactivity to various cephalosporinsESBL can be detected in clinical microbiology (phenotypic) and molecular detection (genotypic)
Recent Therapeutics Policies of Arthritis Rheumatoid (part I) Hendrata Erry Andisari
Denta Journal Kedokteran Gigi Vol 1 No 1 (2018): Oceana Biomedicina Journal Vol 1 Issue (No) 1 January-June 2018
Publisher : Universitas Hang Tuah

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Therapy in RA has undergone many advances today and in line with knowledge of the pathogenesis of RA, the current therapeutic goal is to alter the journey and control the activity of RA disease. Several groups of drugs have been used in RA therapy including non-steroidal anti-inflammatory drugs (NSAIDs), conventional diseasemodifying antirheumatic drugs (DMARDs) as well as biological agents (bDMARD), glucocorticoids and anti-pain medicines. In recent years, the development of biological agents that have specific targets for inflammatory mediators such as interleukin (IL) -1, IL-6 and Tumor Necrosis Factor (TNF) suggests a potent therapeutic effect on RA. In this article will be presented the latest biological agents as the latest therapy on RA.
HIV Infection: Immunopathogenesis and Risk Factor to Fishermen Retno Budiarti
Denta Journal Kedokteran Gigi Vol 1 No 1 (2018): Oceana Biomedicina Journal Vol 1 Issue (No) 1 January-June 2018
Publisher : Universitas Hang Tuah

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AIDS (Acquired Immuno Deficiency Syndrome) caused by HIV (Human Immunodeficiency Virus) infection, is still one of the infectious diseases that causes fatalistic and have not already found a universal and reliable vaccine. As the name given to the virus as well as the disease it causes, the signs and symptoms experienced by the sufferer are persistent and severe disorders of the body's defense mechanism against the disease, or the person's immunological system.Epidemiology of AIDS in Indonesia, which is a tropical country and its territory is mostly sea area still high, even East Java was the highest accumulatively until March 2016. HIV infection itself until March 2016, East Java accumulatively was on the second level after DKI Jakarta. Based on the data of The Ministry of Health during 2014, farmer and fishermen were on the fourth level of AIDS in Indonesia.This mechanism of immune system disorders by HIV is important to explain and understand, so that current researchs, as well as in the future, can solve the problems posed by this viral infection, either by the discovery of vaccines or their preventive measures, formulation of a therapeutic management which is reliable.

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