Media Farmasi Indonesia
Vol. 15 No. 2 (2020): Media Farmasi Indonesia

UJI KANDUNGAN FENOLIK TOTAL DAN AKTIVITAS ANTIBAKTERI EKSTRAK KULIT BUAH ASAM PAYA (Eleiodoxa conferta (Griff.) Burret) TERHADAP Staphylococcus aureus.

Elisabeth SITORUS, Febrina Claudia (Unknown)
Dwi WULANSARI, Endang (Unknown)
SULISTYARINI, Indah (Unknown)



Article Info

Publish Date
30 Oct 2020

Abstract

Asam paya (Eleiodoxa conferta (Griff.) Burret) contains phenolic compounds which can function as antibacterial agents against Staphylococcus aureus. Extraction using soxhlet with multilevel polarity, namely n-hexane and ethanol. The antibacterial activity test by TLC contact-bioautography showed that the phenolic compounds in the ethanol extract had antibacterial activity, and the diffusion test results showed that the ethanol extract had a larger inhibition zone diameter than the n-hexane extract. The total phenolic compound of extract was determined using the Folin-Ciocalteu reagent. The total phenolic compounds of Eleiodoxa conferta (Griff.) Burret. ethanolic extract is 7,326± 0,0989 mg GAE/gram sample. The ethanol extract was fractionated using a separating funnel, followed by purification with preparative TLC. The phenolic isolates obtained were tested for purity by three eluent TLC. The results of antibacterial activity diffution test and TLC contact-bioautography test showed that phenolic isolates had antibacterial activity against Staphylococcus aureus.

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Journal Info

Abbrev

MFI

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology Other

Description

Media Farmasi Indonesia publishes original article in the all scopes of Pharmaceutical Science such as Pharmaceutics, Biopharmaceutics, Drug Delivery System, Chemical Pharmacy, Pharmaceutical Technology, Pharmaceutical Microbiology and Biotechnology, Pharmacology and Toxicology, Pharmacokinetics, ...