JFL : Jurnal Farmasi Lampung
Vol. 10 No. 2 (2021): JFL : Jurnal Farmasi Lampung

AKTIVITAS ANTIFUNGI MINYAK ATSIRI DAUN KEMANGI (Ocimum x africamum Lour.) TERHADAPTrichophyton rubrum dan Trichophyton mentagrophytes

Annisa Mulia Anasis (Program Studi Farmasi Universitas Tulang Bawang)
Mashuri Yusuf (Program Studi Farmasi Universitas Tulang Bawang)
Sigit Prayoga (Program Studi Farmasi Universitas Tulang Bawang)



Article Info

Publish Date
13 Sep 2022

Abstract

Abstract Traditional medicine using natural because it has small side effects and more economical than the synthetic drugs. One of the medicinal plants that for traditional medicine is basil (Ocimum x africamum Lour.).Basil plants contain active compounds such as alkaloids, saponins, flavonoids, triterpenoids, steroids, tannins, eugenol, phenols and essential oils that act as antifungals. Sweet basil essential oil can damage fungal cell membranes so that fungal cell molecules lyse which results in fungal cell death. The purpose of this study was to prove the antifungal activity of sweet basil essential oil as antifungal against T. rubrum and T. mentagrophytes. The essential oil from sweet basil leaves was obtained as much as 18 ml using the steam distillation method. Testing for antifungal activity was carried out using the agar dilution method/well method. The concentrations used in this study were 10%, 20%, 30%, 40%, 100%, positive control using ketoconazole and negative control using aquades with media Potato Dextrose Agar (PDA).Based on the results of research that has been carrier out, basil leaves essential oil has antifungal activity against with the largest inhibition greatest at 100% concentration with an inhibition zone diameter of 15,05 mm for T. rubrum and 19,11 mm for T. mentagrophytes Key words : antifungal, essential oil of sweet basil leaves, Trichophyton rubrum, Trichophyton mentagrophytes

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Journal Info

Abbrev

jfl

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology Public Health

Description

The focus of JFL is to become a media for the publication of articles on Pharmaceutical and related practice-oriented subjects in the pharmaceutical sciences, natural medicine and clinic community. The scope of the journal is Pharmaceutical sciences, its research and its ...