The incidence of dengue hemorrhagic fever (DHF) is a complication caused by the dengue virus and it is primarily transmitted by the Aedes aegypti mosquito. There are 87 cases of DHF incidence at Watujawula health center, Tambolaka city Sub-District, Southwest Sumba District. The purpose of this research was to analyze the relationship between house sanitation and the presence of larvato DFH. An observational analytic survey was used as the type of the studyusing a cross-sectional study design. The study location was in Langga Lero urban village, Southwest Sumba District.The samples of the study were 97 people from Langga Lero urban village as the working area of Watukawula health center. A simple random sampling method was used to determine the samples. Questionnaires, observations, and the analytical method of univariate and bivariate analysis using the Chi-square test with a significance level (0.05) were used as the data collection.The results of the study were found thatthe existenceof significance of DHF between the home environment was P-value = 0,003, water reservoirwas p-value = 0,003, waste management was p-value = 0,00, and the existence of larva was p-value = 0,01. The people need to keep their houses clean by cleaning and closing the water storage, throwing the garbage into its place, giving abate powder in the water storage tank, and doing mosquito nest eradication activity.
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