Jurnal Indah Sains dan Klinis
Vol. 3 No. 2 (2022)

Uji Ekstrak Kulit Buah Mangga Arum Manis dalam Etanol pada Tumbuh Kembang Escherichia coli dan Salmonella typhi

Mandike Ginting (Program Studi Farmasi & Kesehatan Umum, Institut Kesehatan Helvetia, Medan, Indonesia)
Suprianto Suprianto (Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam)
Siti Fatimah Hanum (Program Studi Farmasi & Kesehatan Umum, Institut Kesehatan Helvetia, Medan, Indonesia)
Debi Meilani (Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam)
Maya Sartika (Program Studi Farmasi & Kesehatan Umum, Institut Kesehatan Helvetia, Medan, Indonesia)



Article Info

Publish Date
21 Aug 2021

Abstract

Background: Antibacterial is a substance that can interfere with the growth or even kill bacteria by interfering with harmful microbial metabolites. The skin of the Harum Manis Mango (Mangifera indica L.var. arum sweet) contains flavonoid compounds which are known to have antibacterial activity. Objective: This study aimed to determine the antibacterial activity of the ethanol extract of Harum Manis Mango skin against the antibacterial activity of Escherichia coli and Salmonella typhi. Methods: The research method used in this study was the well diffusion method to determine the antibacterial activity of the ethanol extract of the Harum Manis mango skin Escherichia coli and Salmonella typhi using chloramphenicol 250 mg used as a comparison of antibacterial activity. Results: The results of the antibacterial activity of the ethanolic extract of Harum Manis mango skin against Escherichia coli showed the diameter of the inhibition zone as follows: 20% concentration (12.83 mm), 30% concentration (12.93 mm) and 40% concentration (13.91 mm), while against Salmonella typhi with a concentration of 20% (11.63mm), a concentration of 30% (12.5mm) and a concentration of 40% (13.5mm).Conclusion: The conclusion of this study is that the ethanol extract of the skin of the Harum Manis Mango (Mangifera indica L. var. arum sweet) has antibacterial activity against Escherichia coli and Salmonella typhi bacteria. The most effective concentration against Escherichia coli at concentration of 40% (13.91mm) and Salmonella typhi at a concentration of 40% (13.5mm) with strong inhibition.

Copyrights © 2022






Journal Info

Abbrev

jisk

Publisher

Subject

Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing

Description

Jurnal Indah Sains dan Klinis adalah Jurnal tentang kesehatan yang mencakup sains dan klinis yang diterbitkan oleh Lembaga Penelitian dan Pengabdian pada Masyarakat (LPPM) STIKes Indah Medan yang meliputi kajian Ilmu Farmasi, Kedokteran, Keperawatan, Kebidanan, Kimia, Biologi, Mikrobiologi, Kultur ...