Perbandingan Hasil COVID-19 Metode Rapid Antigen Test dengan PCR: Literature Review

Siti Rachmawati (Program Studi Ilmu Kesehatan Masyarakat Program Magister, Fakultas Kesehatan Masyarakat Universitas Sriwijaya Palembang, Sumatera Selatan, Indonesia)
Yuanita Windusari
Hamzah Hasyim

Jurnal Ilmiah Universitas Batanghari Jambi
Vol 22, No 3 (2022): Oktober

The basis for the identification of SARS-CoV-2 cases in handling the COVID-19 pandemic is Reverse Transcriptasi Polymerase (RT-PCR) and the SARS-CoV-2 specific rapid antigen test. RT-PCR test takes a long time and expensive to get results, while the SARS-CoV-2 rapid antigen test is a simple and fast alternative in getting COVID-19 detection results. The method used is descriptive observational in the form of a literature review by reviewing the existing literature. Several screening and confirmatory tests are available to detect SARS-CoV-2. Screening tests such as the Rapid Antigen Test (RAT) can identify high-risk populations. RAT reduces dependence on RT-PCR, where the cost of the RT-PCR kit and technical expertise is a major concern. Precise and sensitive molecular technique that quantitatively detects viral RNA from clinical specimens. RAT for COVID-19 showed lower sensitivity than RT-PCR for both symptomatic (single or multiple symptoms) and asymptomatic infections.