This research focuses on analyzing the influence of Workload, stress, technical skills, self-efficacy, and social competence on the performance of medical personnel in the era of the Covid-19 pandemic. This research includes quantitative descriptive analysis with a cross-sectional approach. The dependent variables in this study are the performance of medical personnel, while the independent variables are Workload, work stress, technical skills, self-efficacy, and social competence. Sample an in this study is a part of the medical personnel who provide services to a Covid-19 patient ataSukajadi Regional General Hospital, Banyuasin, South Sumatra, which totals 130 people. Take a sample using purposive sampling. Data analysis and processing using the Multiple Linear Regression method. The results showed that Workload had a negative and significant effect on the Performance of Medical Personnel at the Sukajadi Regional General Hospital, Banyuasin, South Sumatra (sig value (0.022) Level of Significant (0.05)), technical Skills have a positive and significant effect on the Performance of Medical Personnel at the Sukajadi Regional General Hospital, Banyuasin, South Sumatra (sig value (0.046)
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