Pro-Life
Vol. 9 No. 3 (2022): November

Potensi Antijamur Ekstrak Andaliman (Zanthoxylum acanthopodium) terhadap Candida albicans

Fri Rahmawati (Departeman Biokimia Kedokteran Fakultas Kedokteran, Universitas Kristen Indonesia)
John Jackson Yang (Departeman Biokimia Kedokteran Fakultas Kedokteran, Universitas Kristen Indonesia, Jakarta)
Irene Rumiris Bavelina (Departeman Biokimia Kedokteran Fakultas Kedokteran, Universitas Kristen Indonesia, Jakarta)



Article Info

Publish Date
09 Jan 2023

Abstract

Andaliman (Zanthoxylum acanthopodium DC) is a plant that grows and is widely used in Sumatra, especially by the Batak tribe (North Sumatra). Andaliman is empirically used for the treatment of diarrhea, toothache, and is a natural food preservative. Resistance increase of antifungal drugs to Candida albicans, so research is needed to find new ingredients that are effective as antifungals. The use of traditional medicines derived from plants can be an alternative for the community as an antifungal. The aim of the research was to determine the class of active compounds and the potential of andaliman fruit extract to inhibit the growth of C. albicans. The extraction process uses the maceration method with 70% ethanol and aquadest as a solvent. The antifungal activity test method used was the disc diffusion method and the phytochemical test using the Harborne method. The concentration of andaliman extract used was 50%, 40%, 30%, 20% and 10%, positive control was fluconazole and negative control was distilled water. The results showed that the andaliman extract was able to inhibit the growth of C. albicans with the lowest concentration of 10%. Andaliman extract (ethanol and aquadest) contains active compounds in the form of flavonoids, tannins, saponins, and steroids.

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Journal Info

Abbrev

prolife

Publisher

Subject

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Education Immunology & microbiology

Description

Ilmu Biologi merupakan salah satu ilmu yang terus bertumbuh dan menjadi bagian yang penting dalam kehidupan. Ilmu Biologi mencakup kajian teori, penelitian hingga pendidikan Biologi menjadi cakupan ilmiah yang terus diteliti dan dikaji hingga memperoleh manfaat bagi kehidupan. Program studi ...