Biology, Medicine, & Natural Product Chemistry
Vol 12, No 1 (2023)

GLUT4 as A Protein Target for T2DM Therapy with Natural Compounds

Sutandar, Vivi Hendra (Unknown)
Saleh, Mgs. Irsan (Unknown)
Maritska, Ziske (Unknown)

Article Info

Publish Date
28 Mar 2023

Abstract

WHO reported 1.9 million death cases of diabetes patients in 2019. Diabetes is caused by damage in the pancreas which resulted in a lack of insulin or insulin resistance. Medication for T2DM mainly focuses on lowering blood glucose and treating affected organs. Current medications are still lacking, thus research is needed in finding novel medications to accommodate T2DM. This paper aims to present the current research on potential plant extract in increasing GLUT4 translocation in diabetes conditions. insulin resistance state affecting GLUT4 translocation which is important in affecting glucose uptake. Some research shows that plant extract proved to be potential in increasing the translocation of GLUT4 and helping lowering blood glucose levels.

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Journal Info
Biology, Medicine, & Natural Product Chemistry
Website

Abbrev

BIOMEDICH

Publisher

Universitas Islam Negeri Sunan Kalijaga Yogyakarta

Subject

Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology Public Health

Description

BIOLOGY, MEDICINE, & NATURAL PRODUCT CHEMISTRY, this journal is published to attract and disseminate innovative and expert findings in the fields of plant, animal, and microorganism secondary metabolite, and also the effect of natural product on biological system as a reference source for ...