Indonesian Journal of Pharmaceutical Education
Vol 3, No 2 (2023): Mei-Agustus 2023

Efektivitas Gel Madu Hutan Akasia terhadap Jumlah Fibroblas pada Luka Sayat Tikus Putih (Rattus novergicus)

Bimby Irenesia (Departemen Fisiologi, Fakultas Kedokteran, Universitas Abdurrab, Kota Pekanbaru, Indonesia)
puan sadila islami (Pendidikan Dokter, Fakultas Kedokteran, Universitas Abdurrab, Kota Pekanbaru, Indonesia)
riski dwi utami (Departemen Fisiologi, Fakultas Kedokteran, Universitas Abdurrab, Kota Pekanbaru, Indonesia)



Article Info

Publish Date
24 May 2023

Abstract

Cuts are wounds caused by sharp objects such as knives, swords, razors and glass. According to data from the Arifin Achmad Regional General Hospital, Riau Province, it was noted that the most common type of wound in sharp violence was a cut (66.7%). When a wound occurs, the wound healing process occurs, namely: inflammation, proliferation, and remodeling. During the proliferative phase, fibroblasts influence the reepithelialization process that closes the wound. Handling cuts using acacia honey because acacia honey in wound healing has anti-inflammatory, antibacterial and antioxidant activities. Knowing the effectiveness of acacia honey gel on the number of fibroblasts in white rat (Rattus novergicus) incision wounds. This type of research is an experimental study design with a randomized posttest only control group design that uses acacia honey on cuts in white rats (Rattus novergicus). There was no significant difference between each treatment group: 20% acacia honey gel, 60% acacia honey gel, 80% acacia honey gel, positive control (povidone iodine) and negative control (gel without honey). Giving acacia honey gel could not increase the number of fibroblasts in white rat (Rattus novergicus) incision wounds.

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Journal Info

Abbrev

ijpe

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemistry Materials Science & Nanotechnology Medicine & Pharmacology

Description

ndonesian Journal of Pharmaceutical Education (IJPE) adalah junal resmi yang diterbitkan oleh Jurusan Farmasi Universitas Negeri Gorontalo yang bekerja sama dengan IAI (Ikatan Apoteker Indonesia) Provinsi Gorontalo. Artikel pada jurnal ini dapat diakses dan unduh secara online oleh publik (open ...