Jurnal Respirasi (JR)
Vol. 9 No. 2 (2023): May 2023

Deciphering the Coagulation Factors in Pulmonary Embolism Incident-Based Thorax Enhanced Chest CT in COVID-19 Patient

Wan Betty Pratiwi (Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.)
Noni Novisari Soeroso (Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.)
Setia Putra Tarigan (Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.)
Muntasir Abdullah (Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.)
Rosita Juwita Sembiring (Department of Clinical Pathology, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.)
Azizah Ghanie Icksan (Department of Radiology, Persahabatan National Respiratory Referral Hospital, Universitas Pembangunan Nasional, Jakarta, Indonesia.)
Netty Delvrita Lubis (Department of Radiology, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.)
Putri Chairani Eyanoer (Department of Community Medicine, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.)



Article Info

Publish Date
31 May 2023

Abstract

Introduction: Pulmonary embolism is associated with coagulopathy in COVID-19. It is one of the causes of death in COVID-19 cases and is often underdiagnosed in Indonesia because computed tomography-pulmonary angiography (CTPA) is not used as the gold standard. T Methods: This study used a prospective analytical design with a cross-sectional approach. The study participants were 45 COVID-19 patients admitted to Santa Elisabeth Hospital, Medan, from January to March 2021.  Patients were identified with moderate to severe degrees of COVID-19 and elevated D-dimer and subsequently instructed to undergo a thorax CT scan with IV contrast. The data was analyzed using dependent t-test statistical analysis. The p-value < 0.05 was noted as significant. Results: Moderate to severe coagulation factor values in COVID-19 patients with mean + SD PT, APTT, D-dimer, fibrinogen, and platelets were 14.11; 30.65; 1172.14; 423.56 and 215.822, respectively. In this study, 22 (48.9%) patients experienced a pulmonary embolism, while the other 23 (51.1%) did not. No significant correlation was found between all coagulation factors and embolism (p > 0.05). The mean + SD well score for pulmonary embolism was 0.23 + 0.57. Conclusion: Pulmonary embolism was detected in 22 patients (48.49%) with moderate to severe COVID-19 who developed hypercoagulation as indicated by the thorax CT scan with IV contrast. This case was quite common. In resource-constrained situations, a thorax CT scan with IV contrast may replace CTPA in diagnosing/detecting the presence of pulmonary embolism.

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Journal Info

Abbrev

JR

Publisher

Subject

Health Professions Medicine & Pharmacology Public Health

Description

Jurnal Respirasi is a National journal in accreditation process managed by Department of Pulmonology & Respiratory Medicine Faculty of Medicine Airlangga University - Dr. Soetomo General Hospital, Surabaya. Publish every January, May, September every year with each of 5 (five) complete texts in ...