Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML)
Vol. 27 No. 2 (2021)

Antibiotics Susceptibility Pattern in Diabetic Ulcer Patients

Mita Rahma Yani (Medical Education Study Program, Faculty of Medicine, Lambung Mangkurat University, Banjarmasin)
Dewi Indah Noviana Pratiwi (Department of Clinical Pathology, Faculty of Medicine, Lambung Mangkurat University/Ulin General Hospital, Banjarmasin)
Rahmiati Rahmiati (Department of Microbiology, Faculty of Medicine, Lambung Mangkurat University, Banjarmasin)
Noor Muthmainah (Department of Microbiology, Faculty of Medicine, Lambung Mangkurat University, Banjarmasin)
Alfi Yasmina (Department of Pharmacology, Faculty of Medicine, Lambung Mangkurat University, Banjarmasin)



Article Info

Publish Date
15 Apr 2021

Abstract

Diabetic ulcers are a chronic complication of diabetes mellitus and have a high risk of infection. Severe ulcer infections are a significant cause of lower-extremity amputations in addition to trauma. Therefore, therapy for diabetic ulcer infections must be performed immediately. This study aimed to determine the bacterial susceptibility pattern to the antibiotic in diabetic ulcer patients. This study was retrospective observational descriptive by taking the results of swab culture and antibiotic susceptibility patterns data in diabetic ulcer patients at Ulin General Hospital, Banjarmasin, in 2016-2018. The results showed 41 (62.1%) monomicrobial infections and 25 (37.9%) polymicrobial infections. The number of Gram-negative bacilli (57.4%) was higher than Gram-positive cocci (42.6%). The most common bacterial isolates on pus culture were Staphylococcus aureus (26.6%), Klebsiella pneumonia (19.1%), and Escherichia coli (12.8%). Antibiotic susceptibility test results showed that Gram-positive bacteria were sensitive to Tigecycline (100%), Nitrofurantoin (96.9%), and Linezolid (96.8%). Gram-negative bacteria were susceptible to Ertapenem (92.7%), Meropenem, and Amikacin (90.6%). S.aureus isolates were sensitive 100% to Meropenem and Tigecycline. K.peneumoniae and E.coli isolates were susceptible 100% to Meropenem and Amikacin. It was concluded in this study that the prevalence of Gram-negative bacteria in diabetic ulcer infection was higher than Gram-positive bacteria. The most common isolated Gram-negative bacteria were K.pneumoniae and E.coli, while the most common Gram-positive bacteria were S.aureus. The most sensitive antibiotics for K.pneumoniae and E.coli were Meropenem and Amikacin, while the most sensitive antibiotics for S.aureus were Linezolid and Tigecycline.

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Journal Info

Abbrev

patologi

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Neuroscience

Description

Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) is a journal published by “Association of Clinical Pathologist” professional association. This journal displays articles in the Clinical Pathology and Medical Laboratory scope. Clinical Pathology has a couple of ...