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All Journal Berkala Kedokteran Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) Homeostasis: Jurnal Mahasiswa Pendidikan Dokter
Muthmainah, Noor
Universitas Lambung Mangkurat
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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POLA KEPEKAAN ISOLAT BAKTERI AEROB PADA RHINOSINUSITIS KRONIS Saputra, Alvin; Qamariah, Nur; Muthmainah, Noor
Berkala Kedokteran Vol 13, No 1 (2017)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v13i1.3446

Abstract

Abstract: Chronic rhinosinusitis is an inflammation of the sinus mucosa caused by viruses or bacteria. Needed research on antibiotic susceptibility of the bacteria that cause chronic rhinosinusitis targeted antibiotics. The purpose of this study was to determine the sensitivity of some selected antibiotics against bacteria of different causes of chronic rhinosinusitis at the Department of Otolaryngology Ulin General Hospital Banjarmasin. This is a descriptive study with cross-sectional approach using diffusion method of Kirby-Bauer zone of inhibition was then compared with standard antibiotics against bacterial antibiotic inhibition zone according to CLSI 2016. The sample in this study were all patients with chronic rhinosinusitis who come for treatment to the Department of Otolaryngology Ulin General Hospital and Moch. Ansari Saleh General Hospital Banjarmasin in the period from June to August 2016. Obtained from 12 samples, 6 samples of Staphylococcus aureus, Staphylococcus epidermis 10 samples, 1 sample Eschirechia coli and 1 sample Bacillus sp. Staphylococcus aureus showed the highest sensitivity to antibiotics cefixime, cefuroxime, ciprofloxacin and clindamycin 66,6%, and the lowest amoxicillin clavulanate 50%. Staphylococcus epidermis showed the highest sensitivity to the antibiotic cefuroxime and clindamycin 100%, cefixime 50% and the lowest amoxicillin-clavulanate and cefuroxime 25%. Escherichia coli showed the highest sensitivity to the antibiotic amoxicillin-clavulanate and cefixime 100%, and the lowest cefuroxime, ciprofloxacin, and clindamycin 0%. Bacillus sp showed the highest sensitivity to the antibiotic cefuroxime, ciprofloxacin, and clindamycin 100% in the lowest 0% for amoxicillin and cefixime. Keywords : chronic rhinosinusitis, sensitivity test, antibiotics Abstrak: Rhinosinusitis kronis adalah peradangan pada mukosa sinus yang disebabkan oleh virus atau bakteri. Perlu adanya penelitian tentang kepekaan antibiotik terhadap kuman penyebab rhinosinusitis kronis agar pemberian antibiotik tepat sasaran. Dengan demikian, tujuan penelitian ini untuk mengetahui kepekaan beberapa antibiotik terpilih terhadap kuman penyabab rhinosinusitis kronis di Bagian THT RSUD Ulin dan RSUD Moch. Ansari Saleh Banjarmasin. Penelitian ini bersifat observasional dengan pendekatan cross sectional menggunakan metode difusi Kirby-Bauer kemudian dibandingkan zona hambat antibiotik terhadap bakteri dengan standar zona hambat antibiotik menurut CLSI 2016. Sampel dalam penelitian ini adalah semua pasien rhinosinusitis kronis yang datang berobat ke Bagian THT RSUD Ulin dan RSUD Moch. Ansari Saleh Banjarmasin pada periode Juni - Agustus 2016. Dari 12 sampel didapatkan, 6 sampel Staphylococcus aureus, 4 sampel Staphylococcus epidermidis, 1 sampel Eschirechia coli dan 1 sampel Bacillus sp. Staphylococcus aureus menujukkan kepekaan tertinggi terhadap antibiotik sefiksim, sefuroksim, siprofloksasim, dan klindamisin sebesar 66,6% serta yang terendah yakni amoksisilin klavulanat sebesar 50%. Staphylococcus epidermidis menujukkan kepekaan tertinggi terhadap antibiotik sefuroksim dan klindamisin sebesar 100%, sefiksim 50% serta yang terendah amoksisilin klavulanat dan sefuroksim sebesar 25%. Eschirechia coli menunjukkan kepekaan tertinggi terhadap antibiotik amoksisilin klavulanat dan sefiksim 100% serta terendah sefuroksim, siprofloksasim dan klindamisin 0%. Bacillus sp menunjukkan kepekaan tertinggi terhadap antibiotik sefuroksim, siprofloksasim, dan klindamisin sebesar 100% serta terendah amoksisilin klavulanat dan sefiksim 0%. Kata-kata kunci : rhinosinusitis kronis, uji kepekaan, antibiotic
HUBUNGAN POLA ASUHAN IBU DENGAN KEJADIAN CACINGAN PADA MURID SDN KUIN SELATAN 5 BANJARMASIN Rabidhamadi, Herry Syawali; Istiana, Istiana; Muthmainah, Noor
Berkala Kedokteran Vol 13, No 1 (2017)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v13i1.3443

Abstract

Abstract: Worm infestation is an infection caused by worm parasites. The infection can be affected by mother care for sanitation and health which are methods to overcome worm transmission. This research aimed to discover the correlation between mother care and worm infestation incident on SDN Kuin Selatan 5 Banjarmasin students in 2016. This was analytic observational research with cross sectional design. There were 95 samples of 1st to 6th grade students chosen by using purposive sampling method. The data was collected by stool examination and questionnaire with chi-square test to analyze it. The result portrayed that there were 6,3% positive worm infected children. Based on analysis test, there is no correlation between mother care and worm infestation incident (p=0,667). Keywords: worm infestation, mother care, SDN Kuin Selatan 5 Abstrak: Infeksi cacingan adalah penyakit infeksi yang disebabkan oleh parasit berupa cacing. Infeksi cacingan dapat dipengaruhi oleh pola asuhan ibu tentang kebersihan dan kesehatan yang merupakan salah satu cara menanggulangi penularan cacingan. Tujuan penelitian adalah untuk mengetahui hubungan antara pola asuhan ibu dengan kejadian cacingan pada murid SDN Kuin Selatan 5 Banjarmasin tahun 2016. Jenis penelitian yang digunakan adalah penelitian observasional analitik dengan pendekatan cross sectional. Jumlah sampel sebanyak 95 anak dari kelas 1-6, dengan teknik pengambilan sampel secara purposive sampling. Pengumpulan data dilakukan dengan pemeriksaan feses dan pengisian kuesioner, sedangkan analisis data menggunakan uji chi square. Hasil penelitian menunjukkan terdapat 6,3% anak positif terinfeksi cacing. Berdasarkan analisis statistik tidak terdapat hubungan pola asuhan ibu terhadap kejadian cacingan (p=0,667). Kata-kata kunci: cacingan, pola asuhan ibu, SDN Kuin Selatan 5
POLA KEPEKAAN ISOLAT BAKTERI AEROB PADA RHINOSINUSITIS KRONIS Alvin Saputra; Nur Qamariah; Noor Muthmainah
Berkala Kedokteran Vol 13, No 1 (2017)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (273.265 KB) | DOI: 10.20527/jbk.v13i1.3446

Abstract

Abstract: Chronic rhinosinusitis is an inflammation of the sinus mucosa caused by viruses or bacteria. Needed research on antibiotic susceptibility of the bacteria that cause chronic rhinosinusitis targeted antibiotics. The purpose of this study was to determine the sensitivity of some selected antibiotics against bacteria of different causes of chronic rhinosinusitis at the Department of Otolaryngology Ulin General Hospital Banjarmasin. This is a descriptive study with cross-sectional approach using diffusion method of Kirby-Bauer zone of inhibition was then compared with standard antibiotics against bacterial antibiotic inhibition zone according to CLSI 2016. The sample in this study were all patients with chronic rhinosinusitis who come for treatment to the Department of Otolaryngology Ulin General Hospital and Moch. Ansari Saleh General Hospital Banjarmasin in the period from June to August 2016. Obtained from 12 samples, 6 samples of Staphylococcus aureus, Staphylococcus epidermis 10 samples, 1 sample Eschirechia coli and 1 sample Bacillus sp. Staphylococcus aureus showed the highest sensitivity to antibiotics cefixime, cefuroxime, ciprofloxacin and clindamycin 66,6%, and the lowest amoxicillin clavulanate 50%. Staphylococcus epidermis showed the highest sensitivity to the antibiotic cefuroxime and clindamycin 100%, cefixime 50% and the lowest amoxicillin-clavulanate and cefuroxime 25%. Escherichia coli showed the highest sensitivity to the antibiotic amoxicillin-clavulanate and cefixime 100%, and the lowest cefuroxime, ciprofloxacin, and clindamycin 0%. Bacillus sp showed the highest sensitivity to the antibiotic cefuroxime, ciprofloxacin, and clindamycin 100% in the lowest 0% for amoxicillin and cefixime. Keywords : chronic rhinosinusitis, sensitivity test, antibiotics Abstrak: Rhinosinusitis kronis adalah peradangan pada mukosa sinus yang disebabkan oleh virus atau bakteri. Perlu adanya penelitian tentang kepekaan antibiotik terhadap kuman penyebab rhinosinusitis kronis agar pemberian antibiotik tepat sasaran. Dengan demikian, tujuan penelitian ini untuk mengetahui kepekaan beberapa antibiotik terpilih terhadap kuman penyabab rhinosinusitis kronis di Bagian THT RSUD Ulin dan RSUD Moch. Ansari Saleh Banjarmasin. Penelitian ini bersifat observasional dengan pendekatan cross sectional menggunakan metode difusi Kirby-Bauer kemudian dibandingkan zona hambat antibiotik terhadap bakteri dengan standar zona hambat antibiotik menurut CLSI 2016. Sampel dalam penelitian ini adalah semua pasien rhinosinusitis kronis yang datang berobat ke Bagian THT RSUD Ulin dan RSUD Moch. Ansari Saleh Banjarmasin pada periode Juni - Agustus 2016. Dari 12 sampel didapatkan, 6 sampel Staphylococcus aureus, 4 sampel Staphylococcus epidermidis, 1 sampel Eschirechia coli dan 1 sampel Bacillus sp. Staphylococcus aureus menujukkan kepekaan tertinggi terhadap antibiotik sefiksim, sefuroksim, siprofloksasim, dan klindamisin sebesar 66,6% serta yang terendah yakni amoksisilin klavulanat sebesar 50%. Staphylococcus epidermidis menujukkan kepekaan tertinggi terhadap antibiotik sefuroksim dan klindamisin sebesar 100%, sefiksim 50% serta yang terendah amoksisilin klavulanat dan sefuroksim sebesar 25%. Eschirechia coli menunjukkan kepekaan tertinggi terhadap antibiotik amoksisilin klavulanat dan sefiksim 100% serta terendah sefuroksim, siprofloksasim dan klindamisin 0%. Bacillus sp menunjukkan kepekaan tertinggi terhadap antibiotik sefuroksim, siprofloksasim, dan klindamisin sebesar 100% serta terendah amoksisilin klavulanat dan sefiksim 0%. Kata-kata kunci : rhinosinusitis kronis, uji kepekaan, antibiotic
Bacteria Sensitivity Pattern of Caesarean Section Wound on Selected Antibiotics in Ulin General Hospital Banjarmasin Nurhafizah Rafiani; Renny Aditya; Noor Muthmainah
Berkala Kedokteran Vol 16, No 2 (2020)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (186.021 KB) | DOI: 10.20527/jbk.v16i2.9208

Abstract

Abstract: A cesarean delivery increases the risk of wound infection it should be prevented by using antibiotics. This study was to determine the pattern of bacterial sensitivity in surgical wounds of cesarean section patients for selected antibiotics, i.e ceftriaxone, cefixime, sulbactam ampicillin, ciprofloxacin, clindamycin and gentamicin.This observational study was conducted at the Ulin Public Hospital in Banjarmasin from July to September 2019. Using a cross sectional approach Samples of bacteria were identidied from 36 that were pusposively sampled, i.e., Staphylococcus aureus, Staphylococcus epidermidis and Escherichia coli. Antibiotic sensitivity test showed that Staphylococcus aureus was sensitive against gentamicin (100%),whereas Staphylococcus epidermidis and Escherichia coli. Were intermediately sensitive towards gentamicin (62.5%) and ceftriaxone (80%) Keywords: Antibiotic susceptibility, caesarean section, surgical wound
HUBUNGAN POLA ASUHAN IBU DENGAN KEJADIAN CACINGAN PADA MURID SDN KUIN SELATAN 5 BANJARMASIN Herry Syawali Rabidhamadi; Istiana Istiana; Noor Muthmainah
Berkala Kedokteran Vol 13, No 1 (2017)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (161.757 KB) | DOI: 10.20527/jbk.v13i1.3443

Abstract

Abstract: Worm infestation is an infection caused by worm parasites. The infection can be affected by mother care for sanitation and health which are methods to overcome worm transmission. This research aimed to discover the correlation between mother care and worm infestation incident on SDN Kuin Selatan 5 Banjarmasin students in 2016. This was analytic observational research with cross sectional design. There were 95 samples of 1st to 6th grade students chosen by using purposive sampling method. The data was collected by stool examination and questionnaire with chi-square test to analyze it. The result portrayed that there were 6,3% positive worm infected children. Based on analysis test, there is no correlation between mother care and worm infestation incident (p=0,667). Keywords: worm infestation, mother care, SDN Kuin Selatan 5 Abstrak: Infeksi cacingan adalah penyakit infeksi yang disebabkan oleh parasit berupa cacing. Infeksi cacingan dapat dipengaruhi oleh pola asuhan ibu tentang kebersihan dan kesehatan yang merupakan salah satu cara menanggulangi penularan cacingan. Tujuan penelitian adalah untuk mengetahui hubungan antara pola asuhan ibu dengan kejadian cacingan pada murid SDN Kuin Selatan 5 Banjarmasin tahun 2016. Jenis penelitian yang digunakan adalah penelitian observasional analitik dengan pendekatan cross sectional. Jumlah sampel sebanyak 95 anak dari kelas 1-6, dengan teknik pengambilan sampel secara purposive sampling. Pengumpulan data dilakukan dengan pemeriksaan feses dan pengisian kuesioner, sedangkan analisis data menggunakan uji chi square. Hasil penelitian menunjukkan terdapat 6,3% anak positif terinfeksi cacing. Berdasarkan analisis statistik tidak terdapat hubungan pola asuhan ibu terhadap kejadian cacingan (p=0,667). Kata-kata kunci: cacingan, pola asuhan ibu, SDN Kuin Selatan 5
Antibiotics Susceptibility Pattern in Diabetic Ulcer Patients Mita Rahma Yani; Dewi Indah Noviana Pratiwi; Rahmiati Rahmiati; Noor Muthmainah; Alfi Yasmina
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 27, No 2 (2021)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v27i2.1652

Abstract

Diabetic ulcers are a chronic complication of diabetes mellitus and have a high risk of infection. Severe ulcer infectionsare a significant cause of lower-extremity amputations in addition to trauma. Therefore, therapy for diabetic ulcer infectionsmust be performed immediately. This study aimed to determine the bacterial susceptibility pattern to the antibiotic indiabetic ulcer patients. This study was retrospective observational descriptive by taking the results of swab culture andantibiotic susceptibility patterns data in diabetic ulcer patients at Ulin General Hospital, Banjarmasin, in 2016-2018. Theresults showed 41 (62.1%) monomicrobial infections and 25 (37.9%) polymicrobial infections. The number of Gram-negativebacilli (57.4%) was higher than Gram-positive cocci (42.6%). The most common bacterial isolates on pus culture wereStaphylococcus aureus (26.6%), Klebsiella pneumonia (19.1%), and Escherichia coli (12.8%). Antibiotic susceptibility testresults showed that Gram-positive bacteria were sensitive to Tigecycline (100%), Nitrofurantoin (96.9%), and Linezolid(96.8%). Gram-negative bacteria were susceptible to Ertapenem (92.7%), Meropenem, and Amikacin (90.6%). S.aureusisolates were sensitive 100% to Meropenem and Tigecycline. K.peneumoniae and E.coli isolates were susceptible 100% toMeropenem and Amikacin. It was concluded in this study that the prevalence of Gram-negative bacteria in diabetic ulcerinfection was higher than Gram-positive bacteria. The most common isolated Gram-negative bacteria were K.pneumoniaeand E.coli, while the most common Gram-positive bacteria were S.aureus. The most sensitive antibiotics for K.pneumoniaeand E.coli were Meropenem and Amikacin, while the most sensitive antibiotics for S.aureus were Linezolid and Tigecycline.
Antibiotic Susceptibility Pattern of Extended-Spectrum Beta-Lactamase-Producing Klebsiella Pneumoniae and Escherichia Coli Erlina Wahyu Elmawati; Dewi Indah Noviana Pratiwi; Noor Muthmainah; Agung Biworo
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 27, No 3 (2021)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v27i3.1634

Abstract

Extended-Spectrum Beta-Lactamase (ESBL) producing bacteria is a type of resistance that leads to complex management of patients in intensive care due to their resistance to first, second, and third-generation Cephalosporin and monobactam antibiotics. The most ESBL-producing bacteria are found in the family Enterobacteriaceae, especially Klebsiella pneumoniae and Escherichia coli. The purpose of this research was to determine the sensitivity pattern of ESBLproducing bacteria in Intensive Care Units (ICUs) of Ulin Hospital, Banjarmasin, in the period of 2016-2018. This research was a descriptive study with a cross-sectional approach using data from the laboratory medical records of patients with positive ESBL in the ICUs of Ulin Hospital, Banjarmasin, between 2016 and 2018. The research sample was taken by the total sampling method. This research obtained 216 isolates of ESBL-producing bacteria consisting of 155 (71.8%) isolates of Klebsiella pneumoniae and 61 (28.2%) Escherichia coli. It was found that the Cephalosporin antibiotics (Cefazolin, Ceftazidime, Ceftriaxone, and Cefepime) and monobactam antibiotic (Aztreonam) had the lowest sensitivity. Aminoglycoside antibiotics (Amikacin), Carbapenem (Ertapenem and Meropenem), and Tetracycline (Tigesycline) were the most sensitive antibiotics. It was concluded that both Klebsiella pneumoniae and Escherichia coli were the most dominant ESBL-producing bacteria and showed good sensitivity to the Amikacin, Ertapenem, Meropenem, and Tigecycline.
Susceptibility Pattern of ESBL Urine Specimens in Non-Intensive Care Room at Ulin General Hospital Alicia Fitri Wulandhany; Dewi Indah Noviana Pratiwi; Noor Muthmainah; Agung Biworo
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 27, No 3 (2021)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v27i3.1637

Abstract

Beta-lactam antibiotic resistance can occur in ESBL-producing bacteria such as E.coli and K.pneumoniae, which can cause UTI. One of the risk factors for infection is the non-intensive care space density level. The objective of this study was to determine the sensitivity pattern of ESBL-producing bacteria in urine specimens of patients in the non-intensive care of Ulin General Hospital, Banjarmasin, in the period of 2016-2018. A descriptive study with a cross-sectional design using data results of urine culture and antibiotic susceptibility patterns data in non-intensive care patients at Ulin General Hospital from 2016 to 2018. The urine test results showed 96 positive isolates of ESBL-producing bacteria, consisting of ESBL-E.coli (69.8%) and ESBL-K.pneumonia (30.2%). Antibiotics with low sensitivity tests were Penicillin, Cephalosporin, Monobactam, and Penicillin/beta-lactam inhibitor combinations. Contrastingly, antibiotics with high sensitivity were Aminoglycoside, Carbapenem, and Glycylcycline. It was concluded from this study that the ESBL-producing bacteria in urine specimens for non-intensive care patients of Banjarmasin Ulin General Hospital in the period of 2016-2018 showed varying sensitivity to antibiotics
Identifikasi Bakteri Kontaminan Udara di Ruang ICU RSUD Idaman Banjarbaru Tahun 2018 Muhammad Syafrie Yunizar; Noor Muthmainah; Rahmiati Rahmiati
Homeostasis Vol 2, No 1 (2019)
Publisher : Homeostasis

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (126.384 KB)

Abstract

Abstract:. The incidence of nosocomial infections in ICU in Indonesia is still high because of the immunocompromaise patients hospitalized in ICU vulnerable exposed to infection. One of transmission of infection is through the air. The aim of this study was to determine the types of air contaminant bacteria in the ICU RSD Idaman Banjarbaru. This study used descriptive method and cross sectional approach. Sampling done by the open plate method using blood agar media and Mac Conkey media. The results of the study found that from 50 bacterial colonies, there were 23 colonies of Staphylococcus aureus (46%), 18 colonies of Escherichia coli (36%), 5 colonies of Staphylococcus epidermidis (10%), and 4 colonies of Salmonella typhii (8%). In conclusion, the types of air contaminant bacteria in the ICU RSD Idaman Banjarbaru was found Staphylococcus aureus with the highest proportion of all samples. Keywords: nosocomial infection, air contaminant bacteria, Intensive Care Unit, open plate Abstrak: Kejadian infeksi nosokomial pada ruang ICU di Indonesia masih tinggi karena pasien - pasien imunokompromais yang dirawat di ruang ICU rentan terkena infeksi. Salah satu cara penularan infeksi adalah melalui udara. Penelitian ini bertujuan untuk mengetahui jenis bakteri kontaminan udara di ruang ICU RSD Idaman Banjarbaru. Penelitian ini menggunakan metode deskriptif dan pendekatan cross sectional. Pengambilan sampel dilakukan dengan metode open plate menggunakan media agar darah dan media Mac Conkey. Hasil penelitian ditemukan bahwa dari 50 koloni bakteri terdapat Staphylococcus aureus 23 koloni (46%), Escherichia coli 18 koloni (36%), Staphylococcus epidermidis 5 koloni (10%), dan Salmonella typhii 4 koloni (8%). Simpulan dari penelitian ini adalah ditemukan jenis bakteri kontaminan udara di ruang ICU RSD Idaman Banjarbaru berupa Staphylococcus aureus dengan proporsi tertinggi dari seluruh sampel. Kata-kata kunci: infeksi nosokomial, bakteri kontaminan udara, Intensive Care Unit, open plate
Perbandingan Aktivitas Antibakteri Sediaan Infus dan Sediaan Ekstrak Daun Sungkai (Peronema canescens Jack) terhadap Bakteri Staphylococcus aureus Syaifullah Akbar Pradito; Noor Muthmainah; Agung Biworo
Homeostasis Vol 5, No 1 (2022)
Publisher : Homeostasis

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (240.173 KB)

Abstract

Abstract: Sungkai (Peronema canescens Jack) a herbal medicine often used by natives of Kalimantan Selatan with boiling method to exctract the water from sungkai leaf and its bark. Infusion prepared and etanol extract prepared sungkai leaf contains active substans such as fenols, terpenoids-steroid, tannins, flavonoids, and alkaloids that own an antibacterial activity. This research aim to find out the differences in the bacterial activity of the infusion prepared and etanol exctract prepared sungkai leaf agains the growth of Staphyloccus aureus. This research methods was true experimental with post-test only group design, consist of a variety infusion prepared and etanol extract prepared consentration on 25%, 50%, 75%, and 100%, clindamycin 2 µg as positive control, and aquadest as negative control. The measured paramater was the diameter of the inhibitory zone. Data from this study were analyzed using parametric One-Way ANOVA test, LSD’s Post-hoc test, and independent T test with a 95% confidence level. The inhibitory zone showed in this study from infusion prepared and etanol extract sungkai leaf on concentration 25%, 50%, 75%, and 100% in a row 6,66 mm, 8,45 mm, 10,17 mm, 12,16 mm and 10,19 mm, 12,89 mm, 14,80 mm, 17,72 mm. Diameter of the inhibitory zone were analyzed with One-Way Anova test showed the value of p= 0,000 (p < 0,05). In conclusion, there are significant differences in antibacterial activity between infusion prepared and extract prepared sungkai leaf on equal level of concentration agains Staphyloccus aureus. Keywords:  etanol extract, infusion, P. canescens Jack, S. aureus Abstrak: Sungkai (Peronema canescens Jack) merupakan tanaman yang sering dimanfaatkan masyarakat Kalimantan Selatan sebagai obat herbal dengan  mengambil air hasil rebusan daun maupun kulit batang sungkai. Sediaan infus dan ekstrak etanol daun sungkai memiliki senyawa aktif saponin, flavonoid, alkaloid, terpenoid-steroid, fenolik, dan tanin yang diketahui bersifat antibakteri. Penelitian ini dilakukan untuk mengetahui perbedaan antibakteri infus dan ekstrak etanol daun sungkai dalam menghambat S. aureus. Metode yang digunakan adalah true experimental dengan post-test only with control group design, variabel yang diuji yaitu variasi infus dan ekstrak etanol konsentrasi 25%, 50%, 75%, 100%, kontrol postitif klindamisin 2 µg, dan kontrol negatif aquadest. Hasil data yang ditabulasi adalah diameter zona hambat. Data dianalisis dengan uji One-way ANOVA, Uji Post-hoc LSD, dan Uji T Independent dengan tingkat kepercayaan 95%. Hasil pemeriksaan zona hambat sediaan infus dan sediaan ekstrak etanol daun sungkai pada konsentrasi 25%, 50%, 75%, dan 100% berturut-turut sebesar 6,66 mm, 8,45 mm, 10,17 mm, dan 12,16 mm dan 10,19 mm, 12,89 mm, 14,80 mm, dan 17,72 mm. Didapatkan nilai dari uji One-way Anova terhadap diameter zona hambat sebesar nilai p = 0,000 (p < 0,05). Kesimpulan penelitian ini yaitu terdapat perbedaan bermakna aktivitas antibakteri antara sediaan infus dengan sediaan ekstrak daun sungkai pada perlakuan konsenstrasi yang sama terhadap S. aureus. Kata-kata kunci:  ekstrak etanol, infus, P. canescens Jack, S. aureus
Co-Authors Achmad Rofii Agnes Angelina Laila Cibro Agung Biworo Agung Biworo Agung Biworo Agung Biworo Agung Biworo Agung Biworo Alfi Yasmina Alicia Fitri Wulandhany Alvin Saputra Alya Maulida Azma Rosida Dewi Indah Noviana Pratiwi Dewi Indah Noviana Pratiwi Dewi Indah Noviana Pratiwi Dewi Indah Noviana Pratiwi Dhio Husmawan Az’har Dini Rizki Aulia Emilia Zulaiha Erlina Wahyu Elmawati Farida Heriyani Herry Syawali Rabidhamadi Ika Kustiyah Oktaviyanti Irhamna Syari Yani Yani Istiana Istiana Istiana Istiana Khatimah, Husnul Larasati Gilang Puji Astuti Lisda Hayatie, Lisda Meitria Syahadatina Noor Mita Rahma Yani Muhammad Azra Inan Abdillah Muhammad Fajariyanoor Muhammad Syafrie Yunizar Nadita Arianti Sumarno Nani Zaitun Nika Sterina Skripsiana Nosi Kusuma Winarno Putri Nur Qamariah Nur Qamariah Nurhafizah Rafiani Rabidhamadi, Herry Syawali Rahmiati Rahmiati Rahmiati Rahmiati Renny Aditya Renny Aditya Rinny Vebliani Risa Dirgagita Rojwa Hafizhah Roselya Elvaniah Rosmitha Monikayani Sandi Paufik Saputra, Alvin Syaifullah Akbar Pradito Triawanti Triawanti