Activity Test Of Ethanol Extract Of Green Sugarcane Stem (Saccharum Officinarum Linn) As Antidiabetic In Male Mice

Prihardini Prihardini (IIK BHAKTI WIYATA KEDIRI)
Dewy Resty Basuki (IIK BHAKTI WIYATA KEDIRI)
Rosa Juwita Hesturini (IIK BHAKTI WIYATA KEDIRI)

Jurnal EduHealth
Vol. 14 No. 02 (2023): Periode April-June, 2023

Diabetes Mellitus is a metabolic disorder characterized by an increase in blood sugar levels caused by the body's inability to produce insulin. One of the non-pharmacological therapies is by utilizing herbal plants such as green sugarcane stalks (Saccarum officinarum L.). Research objective: to find out whether administration of green sugarcane stem extract can reduce alloxan-induced blood glucose levels in mice. Research method: experimental using male males as test animals totaling 25 animals which were divided into 5 groups, namely the negative control group, positive control, a sample group of 100 mg/kg, 125 mg/kg, and 250 mg/kg. Data were analyzed by one-way ANOVA test and continued with the LSD test. The results of the study at a dose of 125 mg/kg BW optimally reduce blood glucose level.