<![CDATA[Background: Low Back Pain is pain, aches and pains that occur in the lower back area and can be local pain or radicular pain. Acupuncture is a non-pharmacological therapy that can be used as an option to treat low back pain. This study aims to examine the effectiveness of acupuncture and sham acupuncture on reducing pain in cases of low back pain.Subjects and Method: Meta-analysis was carried out with PICO as follows: The population in this study were patients with low back pain with an age range of 20-95 years. Intervention in the form of acupuncture therapy. Comparison in the form of sham acupuncture. Outcome in the form of pain scale. A meta-analysis study was applied to this study with electronic data sources Clinical Key, Google Scholar, MEDLINE/PubMed, Science Direct, Scopus, and Springer. The article used is a full-text article with a Randomized Control Trial (RCT) study design. There are 9 articles used in this study. Articles were analyzed using the Review Manager 5.3 application. The results of this study aim to determine the Standardized Mean difference (SMD) and the heterogeneity of the research sample.Results: The heterogeneity in the results of this study was I^2=79%; p < 0.001, so it was analyzed by Random Effects Model (REM). Acupuncture was more effective in reducing pain than sham/placebo acupuncture, with a statistical significance of (SMD -0.59; 95% CI = -0.88 to -0.30; p<0.001.Conclusion: Acupuncture is more effective than sham/placebo acupuncture in reducing pain scale in cases of low back pain.Keywords: Acupuncture, Sham Acupuncture, Low Back PainCorrespondence: Nurtama Aditya Nugraha. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: nurtamaaditya@gmail.com. Mobile: +6282220212767.Indonesian Journal of Medicine (2021), 06(03): 336-346https://doi.org/10.26911/theijmed.2021.06.03.11 ]]>
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