Journal of Clinical Microbiology and Infectious Diseases
Vol. 1 No. 1 (2021): Available Online: June 2021

Urinary Tract Infection (UTI) caused by Extended-Spectrum Beta-Lactamase (ESBL)-producing Enterobacteriaceae: a case series

Qonita Imma Irfani (Microbiology Department, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia)
Dessy Kurnia Sari (Microbiology Department, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia)
Dewi Purbaningsih (Microbiology Department, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia)
Tri Wibawa (Microbiology Department, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia)
Titik Nuryastuti (Microbiology Department, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia)



Article Info

Publish Date
28 Jun 2021

Abstract

Introduction: A urinary tract infection (UTI) is an infection in any part of the urinary system, occurring in the kidneys, bladder, ureters, and urethra. UTI incidence in Indonesia was high enough. The prevalence of UTI in the community enhances in line with the increase of age. 40-60 years had a prevalence rate of 3.2%, while at the age of  ≥65, a UTI had a prevalence rate of 20%. UTIs are among the most common infections in humans. Enterobacteria that produce extended-spectrum beta-lactamase (ESBL) is one of the most frequent causes. Prevalence of the ESBL bacterial infection is developing due to the widespread prescription of antibiotics around the world. Thus, our articles established several UTI cases of various ages and their antibiotic susceptibility. Case Description: This case report series presents eight cases describing a UTI caused by Enterobacteriaceae producing ESBL in various ages. Data were collected retrospectively from secondary sources of laboratory results. Patient baby-child mostly had a history of sepsis. Other than that patient had hydronephrosis kidney, seizure, fever. On the other hand, the patient's old man and woman had a history of fever, shock spinal and fracture, malignancy. All patients were tested for antibiotic susceptibility and mostly still sensitive with amikacin, meropenem, nitrofurantoin, and fosfomycin. Conclusions: Our case series established that patients with UTI were mainly still sensitive to amikacin, meropenem, nitrofurantoin, and fosfomycin. We should implement and maintain contact precautions throughout the hospital wards to prevent the transmission of ESBL infections.

Copyrights © 2021






Journal Info

Abbrev

JCMID

Publisher

Subject

Immunology & microbiology

Description

Journal of Clinical Microbiology and Infectious Diseases; peer-reviewed journal aiming to communicate high-quality research articles, reviews, and general articles in the field. JCMID publishes articles that encompass basic research/clinical studies related to microbiology and infectious disease. ...