Indonesian Journal for Health Sciences (IJHS)
Vol 7, No 2 (2023): September

GENETICS OF DEMENTIA: THE CANDIDATE GENES AND AVAILABLE GENETIC TESTINGS

Ziske Maritska (Universitas Sriwijaya)
Diah Andini (Universitas Sriwijaya)
Febryana Ramadhani Machyar (Universitas Sriwijaya)
Rachmat Taufan (Universitas Sriwijaya)
Try Merdeka Puri (Universitas Sriwijaya)
Tryvanie R Putra (Universitas Sriwijaya)
Uswati Uswati (Universitas Sriwijaya)
Bintang Arroyantri Prananjaya (Universitas Sriwijaya)
Rini Nindela (Universitas Sriwijaya)
Nita Parisa (Universitas Sriwijaya)



Article Info

Publish Date
20 Sep 2023

Abstract

When dementia is present, a person's memory, reasoning, behavior, and even their capacity to carry out day-to-day chores can all become distorted. This syndrome remains present and actually worsens as time passes. It's possible that synapse loss, death and dysfunction of brain cells, gliosis, and inflammation are all factors in the progression of dementia. The clinical syndrome, age, and a history of the ailment in the patient's family should dictate the choices made about counseling and testing. Dementia is known as a multifactorial condition, brought on by the combination of strong genetic factors and environmental factors. There are several candidate genesĀ  associated with Dementia; APP, PSEN1, and PSEN2 genes, in addition to the GRN and MAPT genes. This literatura review provide insight on the genetic of Dementia, particularly in the genetic causes and testings

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Journal Info

Abbrev

IJHS

Publisher

Subject

Nursing Public Health

Description

The Indonesia Journal for Health Sciences publishes articles that report novel findings of health in the areas of : Nursing Midwifery Public health Medicine Pharmacy Biochemistry Molecular biology related drug ...