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All Journal Indonesian Journal for Health Sciences (IJHS)
Diah Andini
Universitas Sriwijaya
Nursing Public Health

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GENETICS OF DEMENTIA: THE CANDIDATE GENES AND AVAILABLE GENETIC TESTINGS Ziske Maritska; Diah Andini; Febryana Ramadhani Machyar; Rachmat Taufan; Try Merdeka Puri; Tryvanie R Putra; Uswati Uswati; Bintang Arroyantri Prananjaya; Rini Nindela; Nita Parisa
Indonesian Journal for Health Sciences Vol 7, No 2 (2023): September
Publisher : Universitas Muhammadiyah Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24269/ijhs.v7i2.6353

Abstract

When dementia is present, a person's memory, reasoning, behavior, and even their capacity to carry out day-to-day chores can all become distorted. This syndrome remains present and actually worsens as time passes. It's possible that synapse loss, death and dysfunction of brain cells, gliosis, and inflammation are all factors in the progression of dementia. The clinical syndrome, age, and a history of the ailment in the patient's family should dictate the choices made about counseling and testing. Dementia is known as a multifactorial condition, brought on by the combination of strong genetic factors and environmental factors. There are several candidate genes  associated with Dementia; APP, PSEN1, and PSEN2 genes, in addition to the GRN and MAPT genes. This literatura review provide insight on the genetic of Dementia, particularly in the genetic causes and testings
Co-Authors Bintang Arroyantri Prananjaya Febryana Ramadhani Machyar Nita Parisa Rachmat Taufan Rini Nindela Try Merdeka Puri Tryvanie R Putra Uswati Uswati Ziske Maritska