Religious moderation within the framework of local wisdom is practiced by the indigenous people of the island of Misool Raja Ampat, Southwest Papua. This can be seen in every community activity that always prioritizes mutual respect between religions. This paper describes the practice of religious moderation carried out by the people of Raja Ampat's Misool Island. This research is based on phenomenological research by looking directly at people's lives with a qualitative approach research method. This research shows that the people of the Misool island in their daily life really uphold the value of religious moderation. This can be seen in several traditional parties or religious activities. The people of Misool Island always prioritize harmony and togetherness regardless of religious background and religious affiliation. Religious traditions that have been practiced since ancient times are still the main pattern in maintaining togetherness and peace. So that with strong moderation, people will have a strong emotional relationship with each other. Moreover, the tribes are dominated by indigenous Papuan people. So that this research can be used as an example of moderation literacy based on local wisdom.
                        
                        
                        
                        
                            
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