Mukhtabar: Journal of Medical Laboratory Technology
Vol 1 No 1 (2023): Mukhtabar: Journal of Medical Laboratory Technology (April 2023)

Erythrocyte Index and Mentzer Index in Fathers of Thalassemia Patients

Rhama Adiguna (STIKes Muhammadiyah Ciamis)
Doni Setiawan (STIKes Muhammadiyah Ciamis)
Undang Ruhimat (STIKes Muhammadiyah Ciamis)
Rahayu Nirmatul Mutmainah (STIKes Muhammadiyah Ciamis)



Article Info

Publish Date
14 Apr 2023

Abstract

Background & Objective Thalassemia is a blood disorder caused by genetic factors that cause the globin chain in hemoglobin to not function normally. It is the most common hereditary disease in the world and in Ciamis Regency in 2021 there were 191 patients. Thalassemia prevention is carried out by screening to identify thalassemia carriers. Hematological examination in the form of erythrocyte index (MCV, MCH, MCHC) and mentzer index has been known to determine thalassemia screening.  The purpose of this study was to determine the description of erythrocyte index and mentzer index in thalassemia patient's father. Method The method used in this study is descriptive method. The population in this study were members of POPTI (Parents Association of Thalassemia Patients) Ciamis Regency. The sample in this study were 30 samples. Result Based on the results of the study obtained the results of erythrocyte index (MCV, MCH) low (MCHC) normal and Mentzer index obtained the results of 20 samples (66%) suspected as thalassemia carrier, 5 samples (17%) suspected iron deficiency anemia and according to the reference value there were 5 samples (17%). Conclusion The results of a study conducted on 30 fathers of thalassemia patients showed that 83% of fathers of thalassemia patients had MCV and MCH values below the normal threshold and 73% had normal MCHC values. Furthermore, from the results of the Mentzer index examination, it is known that 66% of the fathers of thalassemia patients are suspected of having minor thalassemia, 17% are suspected of having iron deficiency anemia disorders and 17% have a normal Mentzer index.

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Journal Info

Abbrev

mjmlt

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology

Description

Mukhtabar Journal of Medical Laboratory Technology (MJMLT) is a peer-reviewed journal published by the Research and Community Service Board of STIKes Muhammadiyah Ciamis since 2023. MJMLT is registered with the International Standard Serial Number (ISSN) with e-ISSN: 2987-0224. This journal is also ...