The participation of pregnant women in pregnant women's classes increases mothers' knowledge about the danger signs of pregnancy. Classes for pregnant women at the Krui Health Center run according to a predetermined schedule. However, after evaluating the K4 visit, it was found that the K4 achievement was still below the target of 95%. This study aimed to determine the relationship between maternal participation in pregnant women classes and knowledge about pregnancy and childbirth in the Working Area of ​​the Krui Health Center, Pesisir Barat Regency, in 2023. This type of research is quantitative with a cross-sectional design. The population in this study were all third-trimester pregnant women with gestational age > 36 weeks in the Working Area of ​​the Krui Health Center with a total of 51 people. The sampling technique used is total sampling. Data collection instruments used questionnaires and the MCH book. Data analysis in this study used univariate and bivariate (chi-square). The results of this study indicate that 29 (56.9%) respondents actively attended classes for pregnant women, and 28 (54.9%) respondents had good knowledge. The data analysis results show a relationship between mothers' participation in pregnant women's classes and learning about pregnancy and childbirth in the Working Area of ​​the Krui Health Center, Pesisir Barat Regency, in 2023, with a p-value of 0.042. Pregnant women are expected to actively participate in classes for pregnant women to increase their knowledge about matters in pregnancy and childbirth.
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