This study aimed to know the growth response and proximate value of Porphyridium cruentum cultured in different salinities of 30 ppt, 15 ppt and 0 ppt. Culture media of 30 ppt and 15 ppt salinity were prepared with sterile seawater, while 0 ppt was from sterile aquades. Fertilizer used was KW21 (Daiichi Seimo Co., Ltd., Kumamoto, Japan) with a dose of 1 ml.l-1. All treatments were cultured for 11 days or until the cell reached exponential-stationer phase, then being growth observed and proximate analyzed. The result showed that all treatments gave the same growth pattern. Control 30 ppt had the highest cell density compare to treatments 0 ppt and 15 ppt, while 0 ppt had higher cell density to 15 ppt. The result of ANOVA (95% of significancy) showed that there was no significant different of cell density with value of 0.232. Proximate analysis showed that all treatments had high water content above 95%. The highest value of energy, carbohydrates and crude fiber were found in 0 ppt treatment, while the highest value of protein and ash were found in 30 ppt. The result from ANOVA showed that there was significant difference in proximate value with significancy less than 0.05
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