<![CDATA[Leptospirosis is a public health threat in countries with tropical climates, like Indonesia. Incidents in Central Java Province are still found every year and still threaten the local community. The goal of this study is to find out what connection there is between sewer puddles and mice that have found leptospira bacteria that can cause leptospirosis in the Regencies of Klaten, Sukoharjo, Karanganyar, and Boyolali in Central Java Province. This research uses descriptive analysis, a cross-sectional design study, and the Geographic Information System (GIS) to carry out mapping. From the research results, it was found that the rat species that were positive for leptospira bacteria were Rattus norvegicus (31%), Rattus tanezumi (44.8%), and Rattus argentiventer (24.1%). Apart from that, only the sampling area and the presence of puddles in the gutter had significant results with the mouse PCR results with p<0.002 and p<0.03. Due to this, there are still many mice infected with leptospira bacteria in Central Java Province. For this reason, it is hoped that the public can increase awareness to always maintain a clean environment so that mice cannot breed freely. Apart from that, related agencies can carry out more monitoring of areas where leptospirosis is still endemic.]]>
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