Efektivitas Ceftazidime-Avibactam terhadap Bakteri Gram Negatif Penghasil Enzim Karbapenemase

Ade Dharmawan (Departemen Mikrobiologi Klinik, Fakultas Kedokteran dan Ilmu Kesehatan, Universitas Kristen Krida Wacana, Jakarta, Indonesia)
Nicolas Layanto (Departemen Mikrobiologi Klinik, Fakultas Kedokteran dan Ilmu Kesehatan, Universitas Kristen Krida Wacana, Jakarta, Indonesia)

Jurnal MedScientiae
Vol. 1 No. 1 (2022): August

Antibiotic therapy is a major concern in the health sector. There is an increase in the resistance of gram-negative bacteria that produce carbapenemase enzymes to certain antibiotics, especially the β-lactam group, thus creating a new challenge for the health world to find stronger antibiotics to fight the resistance of these gram-negative bacteria. Currently, there are several new antibiotics that have been approved as treatment options, such as Ceftazidime-Avibactam. It is hoped that this new treatment can be an option, especially for gram-negative bacteria that produce carbapenemase enzymes.