Borneo Journal of Pharmacy
Vol. 5 No. 3 (2022): Borneo Journal of Pharmacy

Taro (Colosia esculenta) Leaves Extract Inhibits Streptococcus mutans ATCC 31987

Ayu Nala El Muna Haerussana (Poltekkes Kemenkes Bandung)
Angreni Ayuhastuti (Poltekkes Kemenkes Bandung)
Siti Fira Yuniar (Poltekkes Kemenkes Bandung)
Hana Alifah Bustami (Poltekkes Kemenkes Bandung)
Widyastiwi Widyastiwi (Poltekkes Kemenkes Bandung)



Article Info

Publish Date
31 Aug 2022

Abstract

Dental caries was the most common disease in both adults and children. Streptococcus mutans is the main bacteria causing plaque formation and was the initiator of dental caries. Antibacterials derived from plants can be used to prevent plaque formation. Taro (Colosia esculenta) has been used in traditional medicine. Antibacterial compounds have been discovered in C. esculenta leaves. This study aimed to determine the ability of C. esculenta leaf ethanol extract to inhibit the growth of S. mutans ATCC 31987. Simplicia preparation, extract preparation, and phytochemical screening was carried out. Then, the antibacterial activity test was performed using the disc diffusion method to determine the zone of inhibition at various concentrations of 10, 20, 30, 40, 50, 60, and 70%. Colosia esculenta leaf ethanol extract contains alkaloids, flavonoids, triterpenoids, saponins, and produces an inhibition zone at each concentration variation. Very strong antibacterial activity was produced at a concentration of 70% at 21.11±0.46 mm, which was higher than the positive control.

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Journal Info

Abbrev

bjop

Publisher

Subject

Medicine & Pharmacology

Description

Borneo Journal of Pharmacy publishes various scientific articles covering Pharmacy and Pharmaceutical Sciences in the field but not limited to: Pharmacology-Toxicology, including pharmacokinetics, pharmacodynamics, pharmacotherapy, and toxicology. Pharmacognosy-Phytochemistry, including ...