Journal Of World Science
Vol. 3 No. 2 (2024): Journal of World Science

Sarcoidosis: Epidemiology, Etiology, Pathogenesis, and Diagnosis

Setiawan, Fachri (Unknown)
Nurwidya, Fariz (Unknown)



Article Info

Publish Date
29 Feb 2024

Abstract

Interstitial lung disease is a lung condition with wide variations. There are over 200 disorders classified under interstitial lung disease, including sarcoidosis. Sarcoidosis is a systemic disease characterized by the formation of non-caseating granulomas involving the lungs, lymphatic system, skin, and eyes. Clinical manifestations of sarcoidosis vary greatly, ranging from asymptomatic to severe symptoms with uncertain prognosis. The cause of sarcoidosis remains unknown, though several hypotheses suggest its association with genetic, environmental, infectious, and autoimmune factors. The main pathogenesis involves the formation of non-caseating granulomas involving various types of innate and adaptive immune cells. Based on its clinical presentation, sarcoidosis is classified into two types: Lofgren syndrome and non-Lofgren syndrome. Diagnosis of this disease can be established through clinical examination, radiological imaging, and biopsy revealing non-caseating granulomas. Corticosteroid therapy remains the primary treatment option, alongside immunosuppressive and biological therapies for advanced-stage sarcoidosis.

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Journal Info

Abbrev

jws

Publisher

Subject

Computer Science & IT Economics, Econometrics & Finance Engineering Health Professions Law, Crime, Criminology & Criminal Justice Social Sciences

Description

Journal Of World Science is a scientific journal in the form of research and can be accessed openly. This journal is published monthly by CV Riviera Publishing. Journal of World Science provides a means for ongoing discussion of relevant issues that fall within the focus and scope of the journal ...