Jurnal Farmasi dan Sains Indonesia (JFSI)
Vol 6 No 2 (2023)

FORMULASI DAN STABILITAS SERUM WAJAH SARANG BURUNG WALET PUTIH (Collocalia fuchiphaga) SEBAGAI ANTIAGING

Olipiya, Olipiya (Unknown)
Nurmaulawati, Rina (Unknown)
Cahyaningrum, Yanuar As’hari (Unknown)



Article Info

Publish Date
11 Jan 2024

Abstract

White swallow's nest (Collocalia fuchiphaga) is known to have benefits as an antioxidant so it can prevent skin aging. Serum preparations have advantages as skin care cosmetics because they contain active substances in high concentrations, are light and easy to apply. This study aims to make formulations, test physical quality, physical stability, irritation in test animals and test antioxidant activity using the DPPH method (2,2-diphenyl-1-picrylhydrazyl) as a facial serum containing white swallow's nest (Collocalia fuchiphaga) . In this study, a facial serum formulation containing white swallow's nest (Collocalia fuchiphaga) was prepared with various concentrations of 10%, 20% and 30%. The results showed that the 3 formulations had good physical quality tests based on the results of tests carried out in accordance with the standards. Based on the results of the physical stability test, the test results on pH, spreadability and viscosity showed no change in storage for 28 days. The antioxidant activity test results of the 3 formulations yielded IC50 values ​​of F1 (52.523 ppm), F2 (52.181 ppm), and F3 (51.165 ppm). The formulation of white swallow's nest serum (Collocalia fuchiphaga) does not cause primary irritation to rabbit test animals. Based on the results of the data analyzed statistically with a confidence level of 95%, the data obtained was p> 0.05 so that the 3 formulas showed no significant difference. It can be concluded from this study that facial serum containing white swallow's nest (Collocalia fuchiphaga) can be used as an antiaging preparation and does not irritate the skin.

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Journal Info

Abbrev

jfsi

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Medicine & Pharmacology Neuroscience

Description

Focus and Scope Jurnal Farmasi & Sains Indonesia is an open-access journal that published twice a year by Sekolah Tinggi Ilmu Farmasi Nusaputera. This journal is a media of research publication on all aspects of pharmaceutical & science that is innovative, creative, original and based on scientific. ...