Malahayati International Journal of Nursing and Health Science
Vol. 7 No. 1 (2024): Volume 7 Number 1

Assessment of anti-inflammatory of stem extract of Musa balbisiana in wound healing on rats (Rattus norvegicus)

Fadhilah Nurul Karimah (Universitas Muhammadiyah Ponorogo)
Sugeng Mashudi (Universitas Muhammadiyah Ponorogo)
Saiful Nurhidayat (Universitas Muhammadiyah Ponorogo)
Auliya Wanda Azzarin (Universitas Muhammadiyah Ponorogo)
Nuraini Khoirotun Amanah (Universitas Muhammadiyah Ponorogo)



Article Info

Publish Date
17 Mar 2024

Abstract

Background: Balbisiana is a plant that contains flavonoids, which are antioxidants with high anti-inflammatory activity. This antioxidant activity can help the wound-healing process. Purpose: To determine the anti-inflammatory effect of balbisiana extract to help wound healing. Method: The study used 15 rats, which were divided into five groups: a positive control group, a negative control group, a 10% balbisiana extract group, a 20% balbisiana extract group, and a 40% balbisiana extract group. Statistical analysis was performed using the Shapiro-Wilk test to test the normality of the distribution of continuous quantitative data. Levene's test was then used to assess the statistical homogeneity of variance between groups. Welch's One-Way ANOVA was used to analyze the data. Post-hoc analysis was performed using the Games-Howell test. Results: The results of the study showed that balbisiana extract had significant anti-inflammatory activity, especially at a concentration of 40%. This was demonstrated by the results of the study, which showed that rats treated with 40% balbisiana extract had significantly improved wound healing compared to the control groups. Conclusion: This study shows that balbisiana extract has anti-inflammatory activity in helping the wound healing process.

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Journal Info

Abbrev

minh

Publisher

Subject

Health Professions Nursing Public Health

Description

Malahayati International Journal of Nursing and Health Science is a peer-reviewed journal and provides a platform to publish areas of nursing and health science. The journal also seeks to advance the quality of research by publishing papers introducing or elaborating on new methods in nursing and ...