Abstract. Retaining talented employees in the competitive pharmaceutical industry becomes crucial for company success. This study explores employee engagement's role as a mediator in the influence of perceived organizational support on pharmaceutical employees' retention. The study method used is quantitative cross-sectional. Purposive sampling was used with 212 employees from private pharmaceutical companies, each with a minimum period of 6 months. Data analysis in research using Mediation Regression Analysis. The mediation analysis results showed p=0.001 (p<0.05) that employee engagement plays a significant role as a partial mediator in the relationship between perceived organizational support and employee retention by 6,6%. This study provides insights into the importance of perceived organizational support and employee retention in enhancing employee engagement, enabling companies to retain talented employees in the pharmaceutical industry.Keywords: employee engagement; perceived organizational support; employee retention
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