Svāsthya: Trends in General Medicine and Public Health
Vol. 1 No. 1 (2024): July 2024

Nephritic syndrome and acute kidney injury following poststreptococcal glomerulonephritis in pediatric patients: A case report

Endah Indriastuti (Faculty of Medicine and Health, Institut Teknologi Sepuluh Nopember)
Rahmah Yasinta Rangkuti (Faculty of Medicine and Health, Institut Teknologi Sepuluh Nopember)
Alvin Hartanto Kurniawan (Department of Clinical Pathology, Faculty of Medicine, Universitas Airlangga)



Article Info

Publish Date
03 Jul 2024

Abstract

Acute kidney injury (AKI) is characterized by an abrupt decrease in glomerular filtration rate, manifesting as an increase in serum creatinine or oliguria. Nephritic syndrome, a manifestation of glomerulonephritis, presents with hematuria, hypertension, decreased urine output, and edema. This case report discusses an 11-year-old Asian boy who presented with decreased urination, shortness of breath, hypertension, and bilateral leg edema. Urinalysis revealed hematuria, proteinuria, and dysmorphic erythrocytes, while serum creatinine was elevated with a decreased estimated glomerular filtration rate (eGFR). The patient had a positive ASTO test, indicating poststreptococcal glomerulonephritis as the underlying cause of nephritic syndrome and AKI. Although most cases of poststreptococcal glomerulonephritis in children have a favorable outcome, some cases can develop into a serious, life-threatening condition that requires careful attention. This case highlights the importance of early detection and management of poststreptococcal glomerulonephritis to prevent progression to nephritic syndrome and AKI, especially in resource-limited settings. Modest examination modalities can facilitate early detection and faster patient management, particularly in developing countries, to reduce the risk of mortality associated with severe AKI in pediatric patients.

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Journal Info

Abbrev

Svasthya

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Description

Svāsthya: Trends in General Medicine and Public Health is a multidisciplinary journal and it is published six times (January, March, May, July, September, and November) a year. The objective is to promote articles on general medicine, infection, public health, Global health Infection, Tropical ...