Tuberculosis (TB) is an infectious disease that is one of the ten leading causes of death in the world. Indonesia is a country with the second-highest number of TB sufferers in the world. This study aims to identify areas with a high and low relative risk (RR) of TB by using the Bayesian Spatial Conditional Autoregressive (CAR) Besag-York-MolliŃ (BYM) and Leroux models. TB case data in every 24 districts/cities in South Sulawesi province in 2020 is used. The best model was selected based on three criteria, namely Deviance Information Criteria (DIC) and Watanabe Akaike Information Criteria (WAIC). The results show that the Bayesian Spatial CAR BYM and CAR Leroux with hyperprior IG (0.5; 0.0005) are the best models that have the same RR value. Makassar City is the area with the highest RR value (1.70) which indicates that Makassar City has a TB risk 70% higher than the average. On the other hand, the Toraja district has the lowest TB risk (0.43) which indicates that Toraja has a TB risk 43% lower than the average.
                        
                        
                        
                        
                            
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