Jurnal Aisyah : Jurnal Ilmu Kesehatan
Vol 9, No 1 (2024): March 2024

Comparative Analysis of En-Bloc and Conventional Transurethral Resection of Bladder Tumor (TURBT) for Non-Muscle Invasive Bladder Cancer: A Systematic Review and Meta-Analysis

Reynaldo, Reynaldo (Unknown)
Monoarfa, Richard Arie (Unknown)
Duha, Diki Arma (Unknown)



Article Info

Publish Date
14 Mar 2024

Abstract

In order to treat non-muscle invasive bladder cancer, this study will compare and contrast conventional transurethral resection of bladder tumors (TURBT) with En-bloc resection (ERBT). It will also assess the efficacy, safety, and recurrence rates of these two methods. We searched PubMed and Sience Direct for relevant articles published between 2013 and 2023. Articles from randomized controlled trials, retrospective analyses, and prospective studies comparing non-muscle invasive bladder cancer therapies employing en bloc versus conventional TURBT are included in this analysis. Measuring effect size was done using Mean Difference (MD) and Odd Ratio (OR) with 95% CI. There is statistical significance when the p-value is less than 0.05. Fourteen studies were eligible for inclusion. With fewer tumor recurrences (OR 0.66; 95% [CI]  0.52, 0.84; I2 = 6%; P = 0.0007), ERBT proved to be superior to TURBT. There was a decrease in the occurrence of perioperative complications and outcomes associated with ERBT, including bladder perforation and obturator nerve injury.  According to the fourteen articles that were included, patients receiving ERBT experienced much fewer complications, recurrences, hospital stays, and catheterization time than those receiving conventional TURBT.

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Journal Info

Abbrev

jika

Publisher

Subject

Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

Description

Jurnal Aisyah: Jurnal Ilmu Kesehatan (JIKA), with registered number ISSN 2502-4825 (Print) and ISSN 2502-9495 (Online), is an international peer-reviewed journal published two times a year (June and December) by Universitas Aisyah Pringsewu (UAP) Lampung. JIKA is intended to be the journal for ...