Biology, Medicine, & Natural Product Chemistry
Vol 13, No 1 (2024)

Antiepileptic Potential of Justicia insularis Leaf Extract in Swiss Mice

Elkanah, Nancy (Unknown)
Nnumolu, Michael Chuks (Unknown)
Okokon, Jude Effiom (Unknown)
Ise, Uduak Peter (Unknown)



Article Info

Publish Date
08 Aug 2024

Abstract

Epilepsy is a prevalent neurological condition characterized by repetitive seizures, necessitating the exploration of efficacious treatments. Justicia insularis, a plant with a historical use in treating convulsions and epilepsy, has garnered attention as a potential antiepileptic agent. This study aimed to investigate the antiepileptic properties of Justicia insularis leaf extract, focusing on generated seizure models in mice. The analysis of variance (ANOVA), specifically one-way ANOVA, was utilized to assess the statistical significance of the data. Seizure models were employed to evaluate the antiepileptic effects of Justicia insularis leaf extract. The p-values obtained from the one-way ANOVA were significant, with values of ap<0.005, bp<0.01, and cp<0.001. These results suggest the statistical significance of the observed effects in the seizure models. This study provides valuable insights into the therapeutic potential of Justicia insularis leaf extract as a treatment for epilepsy. The significant findings underscore the importance of further research into the use of natural medicines for managing epilepsy, potentially offering new avenues for treatment.

Copyrights © 2024






Journal Info

Abbrev

BIOMEDICH

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology Public Health

Description

BIOLOGY, MEDICINE, & NATURAL PRODUCT CHEMISTRY, this journal is published to attract and disseminate innovative and expert findings in the fields of plant, animal, and microorganism secondary metabolite, and also the effect of natural product on biological system as a reference source for ...