Lemon cui (Citrus microcarpha Bunge) also called lemon fish or lemon kalamansi is a type of local orange which the majority grows in the North Sulawesi area. The purpose of this study was to determine the antioxidant activity of the lemon cui juice sheet mask formula. This research method began with the freeze-drying method until lyophilizate of lemon cui juice was obtained followed by sheet mask formulation with concentration variations in F1 (0.5%), F2 (1%) and F3 (1.5%) and testing antioxidant activity against DPPH radicals analyzed using a UV-Vis spectrophotometer at a wavelength of 505 nm. The results of the antioxidant activity test on lyophilizate of lemon juice cui obtained an average IC50 value of 13.67 μg/mL which is classified as very strong. The results of the antioxidant activity test on lyophilizate of lemon juice cui obtained an average IC50 value of 13.67 μg / mL which is classified as very strong. The results of the antioxidant activity test on each formula on F1 (0.5%) obtained an average IC50 value of 54.338 μg / mL classified as strong, F2 (1%) obtained an average value of IC50 of 31.963 μg / mL classified as very strong and F3 (1.5%) obtained an average value of IC50 of 23.439 μg / mL classified as very strong. The results of the antioxidant activity test show that the lemon juice cui sheet mask formula can also have potential as an antiaging.Keywords: Lemon Cui (Citrus microcarpha Bunge); Antioxidant; Sheet Mask
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