The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy
Vol 25, No 2 (2024): VOLUME 25, NUMBER 2, August, 2024

Composition and Diversity of Intestinal Microbiota in Colorectal Cancer and Potential Utilization in Diagnosis and Therapy

Darnindro, Nikko (Unknown)



Article Info

Publish Date
23 Jul 2024

Abstract

Colorectal cancer is the third most common malignancy and the fourth most common malignancy causing death in the world. The development of colorectal cancer is influenced by several factors, including external, internal environmental, and genetic factors. One of the environmental factors recently known to be associated with colorectal cancer is gut microbiota. Generally, gut microbiota has various functions and is influenced by several factors, such as food, drugs, activities, habits, and diseases. Microbiota may become imbalanced, otherwise known as dysbiosis, which may lead to several changes and disturbances that can initiate the development of malignancy. There were differences in the composition and diversity of the types of microbiota in colorectal cancer patients. This difference has the potential to be used as a diagnostic marker and also the development of treatment in patients with colorectal cancer.Keywords: gut microbiota, colorectal cancer, diversity, abundance

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Journal Info

Abbrev

jghe

Publisher

Subject

Medicine & Pharmacology

Description

The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy is an academic journal which has been published since 2000 and owned by 3 Societies: The Indonesian Society of Gastroenterology; Indonesian Association for the Study of the Liver; The Indonesian Society for Digestive ...