International Journal of Biosciences and Biotechnology
Vol 11 No 2 (2024): International Journal of Biosciences and Biotechnology

Phytochemical Screening and Acute Toxicity Test of Caulerpa lentillifera J. Agardh Infusion Extract on Mice (Mus musculus L.)

Adiyanti, Sekar (Unknown)
Phabiola, Trisna Agung (Unknown)
Sutari, Ni Wayan Sri (Unknown)



Article Info

Publish Date
30 Apr 2024

Abstract

Caulerpa lentillifera has ingredients that are beneficial for health, such as anti-cancer, antioxidant, anti-diabetic, and immunostimulatory effects. This study was aimed to determine the content of phytochemical compounds and the LD50 acute toxicity dose of C. lentillifera infusion extracts on mice for their utilization as food or medicine. The phytochemical screening was done with a qualitative method. Twenty-five mice have been used for the acute toxicity test and divided into five groups of treatment (Control; 375 mg/kg BW; 750 mg/kg BW; 1.500 mg/kg BW; 3.000 mg/kg BW C. lentillifera infusion extracts orally). Symptoms of toxicity and mortality were observed 24 hours after treatment, and body weight was observed for seven days. The phytochemical screening result showed that the C. lentillifera infusion extracts contained alkaloids, saponins, and tannins. Acute toxicity tests showed no mortality in all treatment groups. Thus, the LD50 value could not be obtained and was classified as non-toxic.

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Journal Info

Abbrev

jbb

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Environmental Science

Description

International Journal of Biosciences and Biotechnology provides a unique venue for publishing original researches in biosciences and biotechnology, and ensures that authors could reach the widest possible audience. It publishes both full-length articles and short communications on all aspects of ...