Communications in Science and Technology
Vol 9 No 1 (2024)

Synthesis and characterization of hydroxyapatite/SiO2/gelatin composites as bone scaffold candidates

Wahda, Indah (Unknown)
Syaharuddin Kasim (Unknown)
Maming (Unknown)
Hasnah Natsir (Unknown)
St Fauziah (Unknown)
Yusafir Hala (Unknown)
Andi Muhammad Anshar (Unknown)
Usman, Andriani (Unknown)
Windasari (Unknown)
Indah Raya (Unknown)



Article Info

Publish Date
12 Jul 2024

Abstract

This study aims to determine the characteristics of hydroxyapatite/SiO2/gelatin composites to fulfil the bone scaffold standards. XRF analysis showed that limestone has a high CaO content of 92.89%, allowing it be used for hydroxyapatite synthesis. The wet precipitation method was used to synthesize hydroxyapatite; meanwhile, the freeze-drying method was used to synthesize the hydroxyapatite/SiO2/gelatin scaffold. FTIR analysis confirmed the characteristic peaks, which indicated the presence of compounds of hydroxyapatite (OH- and PO43-), SiO2 (Si-OH and Si-O-Si), and gelatin (N-H, C-H, and C=O). XRD analysis showed 98.1% hydroxyapatite phase and 1.9% SiO2 phase and SEM analysis showed a scaffold pore size of 155-218?m, optimal for cell attachment. Furthermore, mechanical testing resulted in a compressive strength of 1.71 MPa and porosity testing resulted in a porosity of 75%. This characterization showed the potential use of hydroxyapatite/SiO2/gelatin composites as bone scaffolds. This research can enable further development of scaffold materials in the field of tissue engineering.

Copyrights © 2024






Journal Info

Abbrev

cst

Publisher

Subject

Engineering

Description

Communication in Science and Technology [p-ISSN 2502-9258 | e-ISSN 2502-9266] is an international open access journal devoted to various disciplines including social science, natural science, medicine, technology and engineering. CST publishes research articles, reviews and letters in all areas of ...