Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Vol. 1 No. 2 (2021): JULI : Jurnal Ilmu Kedokteran dan Kesehatan Indonesia

Uji Efek Stimulan Sistem Saraf Pusat Dari Ekstrak Etanol Biji Pala (Myristica fragrans H.) Pada Mencit Putih Jantan

Delladari Mayefis (Unknown)
Shinta Sari Dewi (Unknown)
Nurlia Oktaviyanti (Unknown)
Arie Vonikartika (Unknown)



Article Info

Publish Date
31 Jul 2021

Abstract

Research on the effects of central nervous system stimulants from nutmeg (Myristica Fragrans H.) ethanol extract on male white mice has been carried out using the methods of: sleep onset test, hanging test, swimming test, and evacuation test. In this study, the test animals were divided into five groups in which each group consisted of three animals for three experiments, the first group was given a 0.5% NaC CMC suspention, the next three groups were given extracts of nutmeg seed ethanol (Myristica Fragrans H. ) with three variations of doses, namely 150, 300, and 600 mg / Kg BW, the next group as a comparison was given a caffeine solution of 13 mg / kg BW. Each preparation was given orally and then carried out a observation of several test methods. The results showed that the ethanol extract of nutmeg (Pala H.) can provide a good stimulant effect at a dose of 300 mg / kg BW (p <0.05) which was clearly seen in the swimming test and the hanging test method.

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Journal Info

Abbrev

jikki

Publisher

Subject

Health Professions Public Health

Description

Jurnal Ilmu Kedokteran dan Kesehatan Indonesia diterbitkan 3 kali dalam setahun, yaitu pada bulan Maret, Juli dan November. Jurnal Ilmiah Kedokteran dan Kesehatan Indonesia menyajikan hasil penelitian yang bermanfaat bagi dokter, pengambil kebijakan, tenaga kesehatan, dosen serta mahasiswa yang ...