Indonesian Journal of Pharmacy and Natural Product
Vol. 6 No. 02 (2023): Indonesian Journal of Pharmacy and Natural Product

Pengaruh Metode Ekstraksi terhadap Kadar Alkaloid Total Ekstrak Daun Kirinyuh (Chromolaena odorata): Determination of Total Alkaloid Content of Kirinyuh Leaf Extract (Chromolaena odorata) Based on Different Extraction Methods

Hakim, Ali Rakhman (Unknown)
Nayaken, Putri Olivia (Unknown)
Alawiyah, Tuti (Unknown)



Article Info

Publish Date
30 Sep 2023

Abstract

Kirinyuh leave (Chromolaena odorata) was used by the community as a potential plant because it contains many benefits, one of which contains alkaloid compounds. Alkaloids have the ability to help wound healing because the active compounds of the alkaloids have antioxidant activity, so the enhanced wound healing by kirinyuh leaf can be caused by the action of free radicals in increasing levels of antioxidant enzymes. The aim of the study was to determine the total alkaloid content of kirinyuh leaf  leaf extract in each of the extraction methods to be used. In this study, a different extraction method will be used, namely maceration and ultrasonic with ethanol solvent which will be carried out using the UV-Vis spectrophotometry method. The results of measuring the total alkaloid content in each method were the maceration and ultrasonic method consecutive at 8.259% and 5.938%. The conclusion from the research is that the alkaloid content is higher with the maceration method than with the ultrasonic method.   ABSTRAK Daun kirinyuh (Chromolaena odorata) digunakan oleh masyarakat sebagai tanaman yang potensial karena memiliki kandungan yang banyak memberikan manfaat salah satunya mengandung senyawa alkaloid. Alkaloid memiliki kemampuan dalam membantu penyembuhan luka. Senyawa aktif alkaloid memiliki aktivitas sebagai antioksidan. Tujuan penelitian ini adalah untuk menganalisis pengaruh metode ekstraksi terhadap kadar alkaloid total ekstrak daun kirinyuh. Pada penelitian ini menggunakan metode ekstraksi yang berbeda yakni maserasi dan ultrasonik dengan pelarut etanol 96%, kemudian dilakukan analisis kuantitatif alkaloid dengan menggunakan spektrofotometri UV-Vis. Hasil dari analisis kuantitatif alkaloid total pada metode maserasi dan metode ultrasonik berturut-turut adalah sebesar 8,259% dan 5,938%. Simpulan dari penelitian diketahui bahwa kadar alkaloid lebih tinggi dengan metode maserasi dibandingkan metode ultrasonik.

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Journal Info

Abbrev

ijpnp

Publisher

Subject

Medicine & Pharmacology

Description

This journal is aimed as promoting principled approach to research on pharmacy that covers a broad range of topics engaging a good relationship in theoretical and practical. This journal covers: Pharmacology Pharmacognosy Analytical Chemistry Pharmaceutical Technology Social and Management ...