Indonesian Journal of Pharmacy and Natural Product
Vol. 7 No. 01 (2024): Indonesian Journal of Pharmacy and Natural Product

Aktivitas Antibakteri Buah Laban (Vitex pubescens V) yang Tumbuh di Dalam dan di Luar Kawasan Geothermal Ie Seum Aceh Besar terhadap Propionibacterium acnes dan Staphylococcus epidermidis: Antibacterial Activity Of Laban Fruit (Vitex pubescens V) Which Grows In And Outside Geothermal Areas Ie Seum Aceh Besar Against Propionibacterium acnes AND Staphylococcus epidermidis

Rasidah (Unknown)
Jeni Windiyasari (Unknown)
Vonna Aulianshah (Unknown)
Munira (Unknown)
Noni Zakiah (Unknown)
Rini Handayani (Unknown)



Article Info

Publish Date
02 Apr 2024

Abstract

Acne can be caused by clogged skin pores causing red spots, inflammation and infection. Infections of the skin can be caused by the bacteria Propionibacterium acnes and Staphylococcus epidermidis. One plant that has antibacterial potential is laban. Laban plants usually live freely scattered in terrestrial and hilly areas, one of which is in the Ie Seum area in Aceh Besar Regency which is a geothermal area in Aceh. The Ie Seum area has a higher soil pH and temperature compared to other areas (non-geothermal). This study was conducted to determine the difference in antibacterial activity between laban fruit extract (Vitex pubescens V) growing inside and outside the geothermal area of Ie Seum Aceh Besar in inhibiting the growth of Propionibacterium acnes and Staphylococcus epidermidis using disc diffusion method. Microbiological test results obtained the diameter of the inhibitory zone against Propionibacterium acnes and Staphylococcus epidermidis  respectively geothermal laban fruit extract (14.33±1.21 mm and 12.66±1.69 mm) and laban fruit extract outside geothermal (14.83±1.69 mm and 11.41±2.28 mm) and chloramphenicol (19.66±1.88 mm and 22.00±2.50 mm). Anova test results are known to be very influential laban fruit extract (P = 0.000) on the growth of Propionibacterium acnes and Staphylococcus epidermidis. Duncan's further test results found that laban fruit extracts inside and outside the geothermal region had no real difference in inhibiting the growth of Propionibacterium acnes and Staphylococcus epidermidis. The difference in growing place did not provide a difference in antibacterial activity from laban fruit extract (P<0.005).   ABSTRAK Jerawat dapat disebabkan karena tersumbatnya pori-pori kulit sehingga menimbulkan bintik merah, peradangan dan infeksi. Infeksi pada kulit dapat disebabkan oleh bakteri Propionibacterium acnes dan Staphylococcus epidermidis. Salah satu tanaman yang memiliki potensi sebagai antibakteri adalah laban. Tanaman laban biasanya hidup tersebar secara bebas di daerah teresterial dan perbukitan, salah satunya pada kawasan Ie Seum di Kabupaten Aceh Besar yang merupakan daerah geothermal di Aceh. Kawasan Ie Seum memiliki pH tanah dan suhu yang lebih tinggi dibandingkan dengan daerah lainnya (non geothermal). Penelitian ini dilakukan untuk mengetahui perbedaan aktivitas antibakteri antara ekstrak buah laban (Vitex pubescens V) yang tumbuh di dalam dan di luar kawasan geothermal Ie Seum Aceh Besar dalam menghambat pertumbuhan Propionibacterium acnes dan Staphylococcus epidermidis menggunakan metode difusi cakram. Hasil uji mikrobiologi diperoleh diameter zona hambat terhadap Propionibacterium acnes dan Staphylococcus epidermidis berturut-turut ekstrak buah laban geothermal (14,33±1,21 mm dan 12,66±1,69 mm); ekstrak buah laban di luar geothermal (14,83±1,69 mm dan 11,41±2,28 mm) serta kloramfenikol(19,66±1,88 mm dan 22,00±2,50 mm). Hasil uji Anova diketahui ekstrak buah laban sangat berpengaruh (P=0,000) terhadap pertumbuhan Propionibacterium acnes dan Staphylococcus epidermidis. Hasil uji lanjut Duncan diperoleh bahwa ekstrak buah laban di dalam dan di luar kawasan geothermal tidak memiliki perbedaan nyata dalam menghambat pertumbuhan Propionibacterium acnes dan Staphylococcus epidermidis. Perbedaan tempat tumbuh tidak memberikan perbedaan aktivitas antibakteri dari ekstrak buah laban (P<0,005).

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Journal Info

Abbrev

ijpnp

Publisher

Subject

Medicine & Pharmacology

Description

This journal is aimed as promoting principled approach to research on pharmacy that covers a broad range of topics engaging a good relationship in theoretical and practical. This journal covers: Pharmacology Pharmacognosy Analytical Chemistry Pharmaceutical Technology Social and Management ...