Klinikal Sains (Jurnal Analis Kesehatan)
Vol. 12 No. 1 (2024): Juni

DETEKSI GEN TEM DAN GEN SHV PADA Klebsiella pneumoniae PADA SAMPEL URIN PASIEN RAWAT INAP

Ade Irma (Universitas Megarezky)
Ka’bah Ka’bah (Unknown)
Nurul Fathoana (Unknown)



Article Info

Publish Date
07 Jun 2024

Abstract

One of the main causes of healthcare-related infections is the incidence of infections due to Klebsiella pneumonia which commonly causes pneumonia, bacteremia, and urinary tract infections (UTIs). An increased risk of infection with Klebsiella pneumonia bacteria is associated with the emergence of antibiotic resistance genes. The emergence and spread of antibiotic-resistant genes, reduces the chances of treatment and increases mortality and morbidity. This study aimed to detect the TEM gene and SHV gene in Klebsiella pneumonia in the urine of hospitalized patients. The type of research used was laboratory observation with a cross sectional study approach using the Polymerase Chain Reaction method with 15 urine samples of hospitalized patients. The results of this study found 6 positive samples (40%) of Klebsiella pneumonia in the urine of hospitalized patients with a target size of 260bp. Then proceed with the detection of the TEM gene and SHV gene. Found 1 positive sample of TEM gene (16.6%) with a target size of 445bp and 4 positive samples of SHV gene (66.6%) with a target size of 747bp. The conclusion of this study was found TEM and SHV genes in Klebsiella pneumonia that were resistant to sepalosphorin antibiotics in hospitalized patients.

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Journal Info

Abbrev

klinikal

Publisher

Subject

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology

Description

Jurnal klinikal sains program studi analis kesehatan adalah jurnal ilmiah yang membahas tentang kompetensi analis kesehatan yang meliputi kompetensi Mikrobiologi, Hematologi, Parasitologi, Imunoserologi, Toxikologi, dan Kimia Klinik. Jurnal klinikal sains akan terbit setiap enam bulan, dalam satu ...