Jurnal Aisyah : Jurnal Ilmu Kesehatan
Vol 8, No 4: Desember 2023

INVIVO STUDY OF AQUEOUS EXTRACT OF SNAKE FRUIT SEEDS IN FEMALE RATS WITH ANEMIA

Hani Fara Ayu Febyawati (Universitas Sebelas Maret)
Dono Indarto (Universitas Sebelas Maret (UNS))
Selfi Handayani (Universitas Sebelas Maret)



Article Info

Publish Date
13 Dec 2023

Abstract

Anemia remains a global nutritional problem in children, pregnant women and female adolescents because of increasing its prevalence. This study aimed to analyze the effects of aqueoes extract of snake fruit seed (AES) on body weight (BW), body length (BL), body fat percentage (BFP), and wet organ weight in female rats with anemia. This animal experiment used the pre-posttest control group design. A total of 30 female wistar rats with anemia were randomly divided into 5 groups: the negative and positive control groups were given a low iron diet with or without administration of 3.7 mg/200gBW iron supplements, and the treatment (AES1-3) groups were given a low iron diet+AES administration (25,50, and 100 mg/200gBW respectively) for 28 days. Data were analyzed using SPSS 26.0, and STATA MP 17. The average of BW, wet liver and kidney weights in the AES2 group significantly increased, compared to other rat groups. The average of BFP in the AES2 group significantly decreased, compared to the control groups. The average of BL and wet spleen weight did not differ among rat groups. In conclusion, administration of 50 mg/200gBW AES increases BW, wet organ weights, and decreases BFP, but has no effect on BL.

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Journal Info

Abbrev

jika

Publisher

Subject

Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

Description

Jurnal Aisyah: Jurnal Ilmu Kesehatan (JIKA), with registered number ISSN 2502-4825 (Print) and ISSN 2502-9495 (Online), is an international peer-reviewed journal published two times a year (June and December) by Universitas Aisyah Pringsewu (UAP) Lampung. JIKA is intended to be the journal for ...