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All Journal Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Mutiara Medika: Jurnal Kedokteran dan Kesehatan Smart Medical Journal Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan Jurnal Respirologi Indonesia Abdimas Universal JOSSAE (Journal of Sport Science and Education) Jurnal Aisyah : Jurnal Ilmu Kesehatan Smart Society Empowerment Journal Jurnal Kesehatan Proceedings Book of International Conference and Exhibition on The Indonesian Medical Education and Research Institute Media Penelitian dan Pengembangan Kesehatan National Journal of Occupational Health and Safety Folia Medica Indonesiana
Selfi Handayani
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Humanities Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Gambaran Histologis Sel Ginjal Mencit (Mus musculus) yang diinduksi Parasetamol ditambahkan Ekstrak Daun Kemangi (Ocimum sanctum) Basith, Abdul; Listyaningsih, Endang; Handayani, Selfi
Syifa'Medika Vol 7, No 1 (2016): Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan
Publisher : Faculty of Medicine

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32502/sm.v7i1.1388

Abstract

Penggunaan parasetamol sebagai obat analgetik antipiretik dewasa ini semakin meningkat. Parasetamol yang digunakan dengan dosis berlebih dapat menyebabkan efek nefrotoksik. Ekstrak daun kemangi (Ocimum sanctum) mengandung antioksidan yang dapat menangkal radikal bebas dan mengurangi terbentuknya NAPQI yang dihasilkan metabolisme parasetamol. Penelitian ini bertujuan untuk mengetahui gambaran histologis sel ginjal mencit (mus musculus) yang diinduksi parasetamol dan penelitian ini untuk mengetahui efek peningkatan dosis dari ekstrak daun kemangi dapat mengurangi kerusakan sel ginjal mencit yang diinduksi parasetamol. Sampel berupa mencit jantan, galur Swiss webster berumur 2-3 bulan, + 20 gr. Sampel sebanyak 28 ekor dibagi dalam 4 kelompok, masing-masing kelompok terdiri dari 7 ekor mencit. Kelompok kontrol (K) dan kelompok perlakuan 1 (P1), mencit diberi aquades selama 14 hari. Kelompok perlakuan 2 (P2), mencit diberi ekstrak daun kemangi dosis I selama 14 hari. Kelompok perlakuan 3 (P3), mencit diberi ekstrak daun kemangi dosis II. Parasetamol dosis 0,1 ml/ 20 grBB mencit diberikan pada kelompok P1, P2, dan P3 pada hari ke-12, 13, dan 14. Hari ke-15, mencit dikorbankan kemudian ginjal mencit dibuat preparat dengan metode blok parafin dan pengecatan Hematoksilin Eosin (HE). Kerusakan sel ginjal diamati dan dinilai dari gambaran histologis berupa penjumlahan inti piknosis, karioreksis, dan kariolisis. Kerusakan sel ginjal tertinggi pada kelompok P1 (parasetamol) dengan jumlah 75.43 ±5.192 dan kerusakan paling sedikit berada di kelompok K (aquades) dengan jumlah 16.43 ± 2.637.Jumlah kerusakan pada kelompok P2 (dosis I + paracetamol) is 21.29 ± 2.289 dan jumlah kerusakan pada kelompok P2 (dosis II + paracetamol) is 18.29 ± 2.563. Ekstrak daun kemangi dapat mengurangi kerusakan sel ginjal mencit dan peningkatan dosis dari ekstrak daun kemangi dapat mengurangi kerusakan sel ginjal mencit yang diinduksi parasetamol.
Perbedaan Pemilihan Waktu Cold Water Immersion Terhadap Timbulnya Delayed Onset Muscle Soreness Setelah Latihan Submaksimal Arpin, Wilson; Gozali, Dhoni Akbar; Hastami, Yunia; Handayani, Selfi
Journal of Sport Science and Education Vol 5, No 1 (2020)
Publisher : Fakultas Ilmu Olahraga, Universitas Negeri Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26740/jossae.v5n1.p33-38

Abstract

This study aims to knowing the differences in effectiveness of the timing cold water immersion against the onset of delayed onset muscle soreness after submaximal exercise. This research is an experimental study with posttest-only with control group design. The pain of delayed onset muscle soreness measured by Visual Analog Scale. The subjects were 30 samples, which split into 3 groups. Data analysis to determine the result of this study used the one way ANOVA with α determined at 0.05. The result of this study indicate that there are significant differences in each group, the group that received the immersion had a lower pain scale than the control group, also the group that was treated 1 hour after exercise showed better results than the 4 hours, CWI after 1 hour after exercise can inhibit migration of neutrophils which are the main cells of secondary damage that will induce pain. The conclusion of this study is cold water immersion after 1 hour after exercise is better than the 4 hours.
Pendidikan Kesehatan Gigi dan Mulut serta Praktek Menggosok Gigi Pada Anak Berkebutuhan Khusus (ABK) Betty Saptiwi; Risya Cilmiaty; Widia Susanti; Selfi Handayani
Abdimas Universal Vol. 1 No. 2 (2019): Oktober
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Balikpapan (LPPM UNIBA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (484.662 KB) | DOI: 10.36277/abdimasuniversal.v1i2.35

Abstract

Special Needs Children in SLB Anugerah, Colomadu, Karanganyar, Central Java, are still difficult to practice how to brush teeth correctly and still lack of understanding of oral health, so that the hygiene and dental health status and mouth are still lacking. Therefore it is necessary to fix it. The purpose of this activity is to carry out one component of the Higher Education Tri Dharma that is community service. The benefits of this service are for special needs students to increase their knowledge about oral health and improve their skills in brushing their teeth properly. The dedication method is a lecture on how to maintain dental and oral health as well as the practice of brushing teeth along with the target audience, all Special Needs Children in SLB Anugerah, Colomadu, Karanganyar. A total of 52 people were present. The results of the dedication showed that 42.3% of the targets were able to practice brushing teeth with enough categories and 57.7% were still in the poor category. Meanwhile, no one has been categorized as good. The conclusion of this dedication is, the practice of brushing Special Needs Children teeth in SLB Colomadu, Karanganyar is still in the category of sufficient and insufficient so that it is necessary to follow up this service activity by involving parents at home in monitoring the maintenance of dental and oral health of Special Needs Children.
Pembentukan dan Pelatihan Kader Kesehatan Anak Berkebutuhan Khusus tentang Protokol Kesehatan Masa Pandemi COVID-19 Risya Cilmiaty A. R.; Ida Nurwati; Selfi Handayani; Muthmainah Muthmainah; Dyah Ratna Budiani; Betty Saptiwi; Sarsono Sarsono; Martini Martini; Danus Hermawan; Jarot Subandono
Abdimas Universal Vol. 4 No. 1 (2022): April
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Balikpapan (LPPM UNIBA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36277/abdimasuniversal.v4i1.141

Abstract

The incidence of COVID-19 in Indonesia is significantly increasing. In Indonesia, there were 965.283 confirmed cases and 27.453 people died of covid as of January 22, 2021. Meanwhile, the 7.505 confirmed cases and 352 death were from Surakarta. In this pandemic situation, the community must protect itself from being infected by the virus. Prevention is done by implementating the 5M health protocol, which are wearing mask, social distancing, and hand washing. Those health protocols are also part of clean and healthy lifestyle (PHBS). Special needs children (ABK) are those who have different characteristics than any other common children. Special health consideration should be given for those special needs child, including PHBS because of the special needs they are having and probable difficulties into implementing PHBS. The consideration can be given by their teacher, caretaker, parents, or trained social health workers in the hope of special needs children become independent into implementing the PHBS. The aim of this program is implementating social service program and helping special needs children to become independent in implementating PHBS and health protocol. The program was held by lecturing, demonstration, simulation, and supervised practice. This program hopefully will prevent either health issues or prevent the spreading of infective disease, specifically in this pandemic situation.
Electroacupuncture attenuates working memory impairement after chronic stress exposure in rat Selfi Handayani; Nanang Wiyono
JURNAL KEDOKTERAN DAN KESEHATAN Vol 4, No 3 (2017)
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Chronic stress (CS) exposure causes cytogenic and structural changes in the hipocampus which lead to cognitive impairment. Acupuncture has been shown to reduce cortisol secretion and protects hipocampus from stress-related damage. We hypothesize that acupunture can alleviate stress-induced working memory deficit.mthis study aimed to investigate whether electroacupuncture (EA) can improve memory in chronic stress model in rat. This was an experimental study with pretest and postest control group design. Rats were divided randomly into four groups: control group (C), CS group (T1), EA group (T2), and EA plus CS group (T3). Working memory was assessed using Eight-arm radial maze. A marked decrease in working memory was observed in the CS group demonstrated by more working memory correct errors (p=0.020) and incorrect errors (p=0.024) than control group. The CS plus EA rats made fewer working memory correct error (p=0.001) and incorrect error (p=0.000) compared to the CS only group. EA treatment in non-stressed rats did not significantly improve working memory compared to control. Chronic stress decreases working memory in rats. EA treatment at Baihui (DU 20) and Zusanli (ST 36) significantly attenuates stress induced working memory deficits in rats.
Working Posture and Low Back Pain among Female Home Convection Workers: A Cross-Sectional Study Harahap, Aletta Khaerunnisa Putri; Ghozali, Dhoni Akbar; Munawaroh, Siti; Handayani, Selfi; Hastami, Yunia
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 24, No 1 (2024): January
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v24i1.20337

Abstract

Low back pain (LBP) is a significant contributor to global musculoskeletal disorders, often associated with uncomfortable working postures prevalent among home convection workers. This study investigates the correlation between work posture and LBP incidence in 36 female home convection workers aged 20-55, selected through total sampling. This study employed an analytical observational design with a cross-sectional approach. Conducted from March 31 to June 17, 2023, in Sragen, the study utilized RULA with an ordinal scale for posture analysis and the Modified ODI questionnaire, also employing an ordinal scale for LBP measurement. Results revealed 52.78% with low-risk and 47.22% with high-risk postures. Most LBP cases were mild (35 individuals). Kendall’s tau correlation test showed no significant relationship between work posture and LBP incidence (p-value = 0.175, p 0.05). This research concluded that there was no significant relationship between work posture and the incidence of LBP among female home construction workers. However, no significant correlation was found; 47.22% faced a high risk of other musculoskeletal disorders, highlighting the need for immediate posture changes among these workers.
The Relationship between Nutritional Status and the Occurrence of Dental Caries in Elementary School Children at Wonosaren State Elementary School Reflioni, Silvi; Susanti, Widia; Handayani, Selfi; Wulandari, Agustina
Jurnal Kesehatan Vol 17, No 3 (2024): Jurnal Kesehatan
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/jk.v17i3.3914

Abstract

Pendahuluan: Masalah kesehatan gigi dan mulut di provinsi Jawa Tengah masih tinggi yaitu 73,4% pada anak kelompok usia 10-14 tahun dan menempati peringkat ke-22 provinsi di Indonesia. Status gizi, kebersihan rongga mulut, pola makan merupakan faktor-faktor yang dapat menyebabkan karies gigi pada anak. Beberapa penelitian melaporkan terdapat hubungan antara status gizi dengan karies gigi. Penelitian ini bertujuan untuk menggambarkan dan menganalisis hubungan status gizi dengan terjadinya karies gigi pada anak usia sekolah dasar di SD Negeri Wonosaren. Metode: Penelitian ini adalah studi penelitian analitik observasional dengan pendekatan cross-sectional. Penelitian ini dilaksanakan pada bulan Agustus-September 2023. Sampel dipilih secara stratified random sampling sebanyak 100 subjek penelitian. Status gizi diukur dengan teknik antropometri, yaitu menggunakan pengukuran tinggi dan berat badan. Pemeriksaan karies gigi dilakukan dengan cara melakukan inspeksi dan sondasi gigi. Data dianalisis dengan menggunakan Statistical Program for Social Science (SPSS) versi 25. Untuk mengetahui hubungan status gizi dengan terjadinya karies gigi dianalisis dengan uji korelasi pearson. Hasil dinyatakan signifikan apabila p<0.05. Hasil: Uji korelasi pearson menunjukkan tidak ada hubungan antara status gizi (IMT/U) dengan karies gigi (p=0.179). Simpulan: Tidak terdapat hubungan antara status gizi dengan terjadinya karies gigi pada anak usia sekolah dasar di SD Negeri Wonosaren.   Introduction: Dental and oral health problems in Central Java province are still high, namely 73.4% of children aged 10-14 years, and are ranked 22nd province in Indonesia. Nutritional status, oral hygiene, and diet can cause dental caries in children. Several studies report a relationship between nutritional status and dental caries. This study aims to describe and analyze the relationship between nutritional status and the occurrence of dental caries in elementary school-aged children at Wonosaren State Elementary School. Method: This research is an observational analytical study with a cross-sectional approach. This research was carried out in August-September 2023. The sample was selected using stratified random sampling of 100 research subjects. Nutritional status was measured using the BMI/Age technique, obtained from anthropometric weight and height measurements. Weight is measured using a step scale, and height is measured using a microtome. A dental caries examination is carried out by inspection and dental condition. Data were analyzed using the Statistical Program for Social Science (SPSS) version 25. It was analyzed using the Pearson correlation test to determine the relationship between nutritional status and the occurrence of dental caries. Results are declared significant if p<0.05. Results: Pearson correlation test showed no relationship between nutritional status (BMI/U) and dental caries (p=0.179). Conclusion: There is no relationship between nutritional status and the occurrence of dental caries in elementary school-aged children at SD Negeri Wonosaren.
INVIVO STUDY OF AQUEOUS EXTRACT OF SNAKE FRUIT SEEDS IN FEMALE RATS WITH ANEMIA Fara Ayu Febyawati, Hani; Indarto, Dono; Handayani, Selfi
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 8, No 4: Desember 2023
Publisher : Universitas Aisyah Pringsewu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30604/jika.v8i4.2533

Abstract

Anemia remains a global nutritional problem in children, pregnant women and female adolescents because of increasing its prevalence. This study aimed to analyze the effects of aqueoes extract of snake fruit seed (AES) on body weight (BW), body length (BL), body fat percentage (BFP), and wet organ weight in female rats with anemia. This animal experiment used the pre-posttest control group design. A total of 30 female wistar rats with anemia were randomly divided into 5 groups: the negative and positive control groups were given a low iron diet with or without administration of 3.7 mg/200gBW iron supplements, and the treatment (AES1-3) groups were given a low iron diet+AES administration (25,50, and 100 mg/200gBW respectively) for 28 days. Data were analyzed using SPSS 26.0, and STATA MP 17. The average of BW, wet liver and kidney weights in the AES2 group significantly increased, compared to other rat groups. The average of BFP in the AES2 group significantly decreased, compared to the control groups. The average of BL and wet spleen weight did not differ among rat groups. In conclusion, administration of 50 mg/200gBW AES increases BW, wet organ weights, and decreases BFP, but has no effect on BL.
Pemilihan Waktu Ice Compression Pada Timbulnya Delayed Onset Muscle Soreness Setelah Latihan Submaksimal Asyiraq, Muhammad Ferdy; Handayani, Selfi; Ghozali, Dhoni Akbar; Munawaroh, Siti
Journal of Sport Science and Education Vol 7 No 1 (2022)
Publisher : Faculty of Sport and Health Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26740/jossae.v7n1.p1-6

Abstract

The study aims to determine the timing of ice compression on the onset of DOMS after submaximal exercise. This research is experimental with post-test only control group design. Thirty students of the Faculty of Medicine, Sebelas Maret University participated as subjects. Subjects were divided into three groups, control, treatment 1 hour after exercise, and 4 hours after. Submaximal exercise is done by step test. Ice compression was given for 10 minutes on subject’s front thigh muscles. DOMS pain was assessed using the VAS pain scale. The collected data were analyzed using the one way Anova test and continued with the Post Hoc LSD test. The results of the analysis using the one way Anova test showed a significant difference between the three research groups and the Post Hoc test showed no significant difference between two treatment groups, but the treatment 4 hours group had lower pain scale on VAS. Ice compression after 4 hours exercise can inhibit the macrophages which were the main immune cells for inflammatory reactions. From this study, it was concluded that the most effective timing of ice compression on the onset of DOMS was 4 hours after submaximal exercise.
Somatotype and Ratio of Chest Circumference to Height in Asthma Patients and Its Relation to Asthma Control Level Rosyadah, Prima Aprilia; Handayani, Selfi; Hastami, Yunia; Ghozali, Dhoni Akbar
Jurnal Respirologi Indonesia Vol 45 No 1 (2025)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v45i1.450

Abstract

Background: Asthma control level is related to body composition. Somatotype is a body shape classification that is used to measure body composition indirectly using anthropometry. As far as we know, no studies are related to somatotype and asthma control levels. This study aims to describe the somatotype and the ratio of chest circumference to height and its relation to asthma control level. Methods: This research is an observational study at Surakarta in September-December 2022. The subjects were 51 asthma patients under control and met the criteria. Measurement of somatotype and the ratio of chest circumference to height was carried out by anthropometric methods. The Asthma Control Test (ACT) questionnaire assessed the asthma control level. The collected data were analyzed using SPSS 26 software with Fisher’s test and unpaired t-test. Results: out of 51 asthmatic patients, 43 (84,3%) had endomorphic and 8 (15,7%) ectomorphic. Fisher’s test showed no significant relationship between somatotype and asthma control level (P=0.56). Meanwhile, the mean ratio of chest circumference to height in controlled patients was 0.54, while those who were uncontrolled were 0.58. The results of the unpaired t-test showed that there was a significant difference between the ratio of chest circumference to height and asthma control level (P=0.03).   Conclusion: There is no significant relationship between somatotype and asthma control level, but there is a significant relationship between the ratio of chest circumference to height and the asthma control level.
Co-Authors . Balgis . Muthmainah . Muthmainah Achmad Fauzi Kamal Agus Sugeng Riyanto Agustina Wulandari Ahmad Aulia Ahmad Isnaini Shidqi Nurhani Annisa Aghnia Rahma Annisa Budiastuti Arif Setyoko Arpin, Wilson Aryoseto, Lukman Asyiraq, Muhammad Ferdy Balgis . Balgis Balgis Betty Saptiwi Betty Saptiwi Budiono, Enrico Ananda Budiyanti, Novita Danus Hermawan Dhoni Akbar Ghozali Diniyati, Hilda Dono Indarto Dwi rahayu Dyah Ratna Budiani Dyonisa Nasirochmi Pakha Endang listyaningsih Endang Listyaningsih Endang Listyaningsih Enrico Ananda Budiono Fara Ayu Febyawati, Hani Firnadi, Jossefa Gozali, Dhoni Akbar Hakim, Fikar Arsyad Handayani Putri Cahyaningrum Harahap, Aletta Khaerunnisa Putri Harahap, Alida Roswita Hardjono . Hasan Mihardja Hastami, Yunia Hermawan, Danus Hernowo Setyo Utomo Ida Nurwati Ilyas, Muhana Fawwazy Itsna Ulin Nuha Jarot Subandono Jarot Subandono Kiyatno . kusnandar kusnandar Luh Karunia Wahyuni, Luh Karunia Lukman Aryoseto M Abdul Basith Maria Mumtaz Martini Martini Marufah, Siti Muhammad Afif Muhammad Luthfiyanto Muhammad Syauqi Ridhallah Muhana Fawwazy Ilyas Muthmainah Muthmainah Muthmainah Muthmainah Nanang Wiyono Nanang Wiyono Nareswari, Irma Nisa&#039;u Luthfi Nur Azizah Nur Dwi Fajarini Nurhani, Ahmad Isnaini Shidqi Nurwijayanti Paksi Suryo Bawono Rahma, Annisa Aghnia Reflioni, Silvi Retno Asti Werdhani Reyhan Eddy Yunus Ridhallah, Muhammad Syauqi Risya Cilmiaty Risya Cilmiaty A. R. Riyanto, Agus Sugeng Rosyadah, Prima Aprilia Rukmindar, Dion Sarsono Sarsono Shabrina, Syania Siti Munawaroh Siti Munawaroh slamet Riyadi Sunggoro, Agus Jati Susanti, Widia Syania Shabrina Widia Susanti Yundari, Yundari