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All Journal Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Mutiara Medika: Jurnal Kedokteran dan Kesehatan Smart Medical Journal Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan Jurnal SPORTIF : Jurnal Penelitian Pembelajaran Jurnal Respirologi Indonesia Abdimas Universal JOSSAE (Journal of Sport Science and Education) Jurnal Aisyah : Jurnal Ilmu Kesehatan Journal SAGO Gizi dan Kesehatan Ahmar Metakarya: Jurnal Pengabdian Masyarakat Smart Society Empowerment Journal Jurnal Kesehatan Plexus Medical Journal Proceedings Book of International Conference and Exhibition on The Indonesian Medical Education and Research Institute Media Penelitian dan Pengembangan Kesehatan National Journal of Occupational Health and Safety Folia Medica Indonesiana

Selfi Handayani

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Author-ID : 274208

Humanities Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Gambaran Histologis Sel Ginjal Mencit (Mus musculus) yang diinduksi Parasetamol ditambahkan Ekstrak Daun Kemangi (Ocimum sanctum) Basith, Abdul; Listyaningsih, Endang; Handayani, Selfi
Syifa'Medika Vol 7, No 1 (2016): Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan
Publisher : Faculty of Medicine

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32502/sm.v7i1.1388

Penggunaan parasetamol sebagai obat analgetik antipiretik dewasa ini semakin meningkat. Parasetamol yang digunakan dengan dosis berlebih dapat menyebabkan efek nefrotoksik. Ekstrak daun kemangi (Ocimum sanctum) mengandung antioksidan yang dapat menangkal radikal bebas dan mengurangi terbentuknya NAPQI yang dihasilkan metabolisme parasetamol. Penelitian ini bertujuan untuk mengetahui gambaran histologis sel ginjal mencit (mus musculus) yang diinduksi parasetamol dan penelitian ini untuk mengetahui efek peningkatan dosis dari ekstrak daun kemangi dapat mengurangi kerusakan sel ginjal mencit yang diinduksi parasetamol. Sampel berupa mencit jantan, galur Swiss webster berumur 2-3 bulan, + 20 gr. Sampel sebanyak 28 ekor dibagi dalam 4 kelompok, masing-masing kelompok terdiri dari 7 ekor mencit. Kelompok kontrol (K) dan kelompok perlakuan 1 (P1), mencit diberi aquades selama 14 hari. Kelompok perlakuan 2 (P2), mencit diberi ekstrak daun kemangi dosis I selama 14 hari. Kelompok perlakuan 3 (P3), mencit diberi ekstrak daun kemangi dosis II. Parasetamol dosis 0,1 ml/ 20 grBB mencit diberikan pada kelompok P1, P2, dan P3 pada hari ke-12, 13, dan 14. Hari ke-15, mencit dikorbankan kemudian ginjal mencit dibuat preparat dengan metode blok parafin dan pengecatan Hematoksilin Eosin (HE). Kerusakan sel ginjal diamati dan dinilai dari gambaran histologis berupa penjumlahan inti piknosis, karioreksis, dan kariolisis. Kerusakan sel ginjal tertinggi pada kelompok P1 (parasetamol) dengan jumlah 75.43 ±5.192 dan kerusakan paling sedikit berada di kelompok K (aquades) dengan jumlah 16.43 ± 2.637.Jumlah kerusakan pada kelompok P2 (dosis I + paracetamol) is 21.29 ± 2.289 dan jumlah kerusakan pada kelompok P2 (dosis II + paracetamol) is 18.29 ± 2.563. Ekstrak daun kemangi dapat mengurangi kerusakan sel ginjal mencit dan peningkatan dosis dari ekstrak daun kemangi dapat mengurangi kerusakan sel ginjal mencit yang diinduksi parasetamol.

Perbedaan Pemilihan Waktu Cold Water Immersion Terhadap Timbulnya Delayed Onset Muscle Soreness Setelah Latihan Submaksimal Arpin, Wilson; Gozali, Dhoni Akbar; Hastami, Yunia; Handayani, Selfi
Journal of Sport Science and Education Vol 5, No 1 (2020)
Publisher : Fakultas Ilmu Olahraga, Universitas Negeri Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26740/jossae.v5n1.p33-38

This study aims to knowing the differences in effectiveness of the timing cold water immersion against the onset of delayed onset muscle soreness after submaximal exercise. This research is an experimental study with posttest-only with control group design. The pain of delayed onset muscle soreness measured by Visual Analog Scale. The subjects were 30 samples, which split into 3 groups. Data analysis to determine the result of this study used the one way ANOVA with Î± determined at 0.05. The result of this study indicate that there are significant differences in each group, the group that received the immersion had a lower pain scale than the control group, also the group that was treated 1 hour after exercise showed better results than the 4 hours, CWI after 1 hour after exercise can inhibit migration of neutrophils which are the main cells of secondary damage that will induce pain. The conclusion of this study is cold water immersion after 1 hour after exercise is better than the 4 hours.

Pendidikan Kesehatan Gigi dan Mulut serta Praktek Menggosok Gigi Pada Anak Berkebutuhan Khusus (ABK) Betty Saptiwi; Risya Cilmiaty; Widia Susanti; Selfi Handayani
Abdimas Universal Vol. 1 No. 2 (2019): Oktober
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Balikpapan (LPPM UNIBA)

Special Needs Children in SLB Anugerah, Colomadu, Karanganyar, Central Java, are still difficult to practice how to brush teeth correctly and still lack of understanding of oral health, so that the hygiene and dental health status and mouth are still lacking. Therefore it is necessary to fix it. The purpose of this activity is to carry out one component of the Higher Education Tri Dharma that is community service. The benefits of this service are for special needs students to increase their knowledge about oral health and improve their skills in brushing their teeth properly. The dedication method is a lecture on how to maintain dental and oral health as well as the practice of brushing teeth along with the target audience, all Special Needs Children in SLB Anugerah, Colomadu, Karanganyar. A total of 52 people were present. The results of the dedication showed that 42.3% of the targets were able to practice brushing teeth with enough categories and 57.7% were still in the poor category. Meanwhile, no one has been categorized as good. The conclusion of this dedication is, the practice of brushing Special Needs Children teeth in SLB Colomadu, Karanganyar is still in the category of sufficient and insufficient so that it is necessary to follow up this service activity by involving parents at home in monitoring the maintenance of dental and oral health of Special Needs Children.

Pembentukan dan Pelatihan Kader Kesehatan Anak Berkebutuhan Khusus tentang Protokol Kesehatan Masa Pandemi COVID-19 Risya Cilmiaty A. R.; Ida Nurwati; Selfi Handayani; Muthmainah Muthmainah; Dyah Ratna Budiani; Betty Saptiwi; Sarsono Sarsono; Martini Martini; Danus Hermawan; Jarot Subandono
Abdimas Universal Vol. 4 No. 1 (2022): April
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Balikpapan (LPPM UNIBA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36277/abdimasuniversal.v4i1.141

The incidence of COVID-19 in Indonesia is significantly increasing. In Indonesia, there were 965.283 confirmed cases and 27.453 people died of covid as of January 22, 2021. Meanwhile, the 7.505 confirmed cases and 352 death were from Surakarta. In this pandemic situation, the community must protect itself from being infected by the virus. Prevention is done by implementating the 5M health protocol, which are wearing mask, social distancing, and hand washing. Those health protocols are also part of clean and healthy lifestyle (PHBS). Special needs children (ABK) are those who have different characteristics than any other common children. Special health consideration should be given for those special needs child, including PHBS because of the special needs they are having and probable difficulties into implementing PHBS. The consideration can be given by their teacher, caretaker, parents, or trained social health workers in the hope of special needs children become independent into implementing the PHBS. The aim of this program is implementating social service program and helping special needs children to become independent in implementating PHBS and health protocol. The program was held by lecturing, demonstration, simulation, and supervised practice. This program hopefully will prevent either health issues or prevent the spreading of infective disease, specifically in this pandemic situation.

Electroacupuncture attenuates working memory impairement after chronic stress exposure in rat Selfi Handayani; Nanang Wiyono
JURNAL KEDOKTERAN DAN KESEHATAN Vol 4, No 3 (2017)
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar

Chronic stress (CS) exposure causes cytogenic and structural changes in the hipocampus which lead to cognitive impairment. Acupuncture has been shown to reduce cortisol secretion and protects hipocampus from stress-related damage. We hypothesize that acupunture can alleviate stress-induced working memory deficit.mthis study aimed to investigate whether electroacupuncture (EA) can improve memory in chronic stress model in rat. This was an experimental study with pretest and postest control group design. Rats were divided randomly into four groups: control group (C), CS group (T1), EA group (T2), and EA plus CS group (T3). Working memory was assessed using Eight-arm radial maze. A marked decrease in working memory was observed in the CS group demonstrated by more working memory correct errors (p=0.020) and incorrect errors (p=0.024) than control group. The CS plus EA rats made fewer working memory correct error (p=0.001) and incorrect error (p=0.000) compared to the CS only group. EA treatment in non-stressed rats did not significantly improve working memory compared to control. Chronic stress decreases working memory in rats. EA treatment at Baihui (DU 20) and Zusanli (ST 36) significantly attenuates stress induced working memory deficits in rats.

Working Posture and Low Back Pain among Female Home Convection Workers: A Cross-Sectional Study Harahap, Aletta Khaerunnisa Putri; Ghozali, Dhoni Akbar; Munawaroh, Siti; Handayani, Selfi; Hastami, Yunia
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 24, No 1 (2024): January
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v24i1.20337

Low back pain (LBP) is a significant contributor to global musculoskeletal disorders, often associated with uncomfortable working postures prevalent among home convection workers. This study investigates the correlation between work posture and LBP incidence in 36 female home convection workers aged 20-55, selected through total sampling. This study employed an analytical observational design with a cross-sectional approach. Conducted from March 31 to June 17, 2023, in Sragen, the study utilized RULA with an ordinal scale for posture analysis and the Modified ODI questionnaire, also employing an ordinal scale for LBP measurement. Results revealed 52.78% with low-risk and 47.22% with high-risk postures. Most LBP cases were mild (35 individuals). Kendall’s tau correlation test showed no significant relationship between work posture and LBP incidence (p-value = 0.175, p 0.05). This research concluded that there was no significant relationship between work posture and the incidence of LBP among female home construction workers. However, no significant correlation was found; 47.22% faced a high risk of other musculoskeletal disorders, highlighting the need for immediate posture changes among these workers.

Hubungan Indeks Massa Tubuh Dengan VO2Max dan Indeks Kebugaran pada Pemain Sepak Bola Raditya Perdana Aryasatya; Selfi Handayani; Dhoni Akbar Ghozali; Nanang Wiyono
Plexus Medical Journal Vol. 3 No. 3 (2024): Juni
Publisher : Fakultas Kedokteran, Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/plexus.v3i3.618

Pendahuluan: Sepak bola membutuhkan strategi permainan yang baik, kondisi fisik yang prima, dan energi dan tingkat fokus yang tinggi. Maka dari itu, pengukuran VO2Max dan indeks kebugaran penting untuk mempertahankan penampilan dalam setiap momen yang ada tanpa adanya hambatan dan kelelahan yang berarti. Salah satu faktor yang mempengaruhi VO2Max dan indeks kebugaran pemain sepak bola adalah Indeks Massa Tubuh (IMT) sehingga tujuan dari penelitian ini adalah untuk mengetahui apakah terdapat hubungan IMT dengan VO2Max dan indeks kebugaran pada pemain sepak bola. Metode: Metode penelitian yang digunakan adalah observasional analitik cross-sectional dengan populasi sebanyak 51 pemain usia 10-19 tahun, lalu dipilih sampel menggunakan purposive sampling dan jumlah sampel dihitung dengan rumus Slovin dengan tingkat kepercayaan 95% dan tingkat kesalahan 5% sehingga diperoleh 45 sampel. Pengukuran IMT menggunakan berat badan melalui timbangan dan tinggi badan melalui microtoise. Pengukuran VO2Max menggunakan Cooper Test-12 Minute Run. Pengukuran indeks kebugaran menggunakan Tes Kesegaran Jasmani Indonesia (TKJI). Uji korelasi menggunakan Uji Spearman’s rho yang dilalui oleh Uji Normalitas Shapiro-Wilk dan Uji Linearitas ANOVA Table. Hasil: Diperoleh koefisien korelasi ρ=-0.041 dan signifikansi Sig. (2-tailed) p=0.787 untuk hubungan antara IMT dengan VO2Max serta diperoleh koefisien korelasi ρ=0.104 dan signifikansi Sig. (2-tailed) p=0.495 untuk hubungan antara IMT dengan indeks kebugaran. Kesimpulan: Tidak terdapat hubungan antara IMT dengan VO2Max dan tidak terdapat hubungan antara IMT dengan indeks kebugaran.

The Relationship between Nutritional Status and the Occurrence of Dental Caries in Elementary School Children at Wonosaren State Elementary School Reflioni, Silvi; Susanti, Widia; Handayani, Selfi; Wulandari, Agustina
Jurnal Kesehatan Vol 17, No 3 (2024): Jurnal Kesehatan
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/jk.v17i3.3914

Pendahuluan: Masalah kesehatan gigi dan mulut di provinsi Jawa Tengah masih tinggi yaitu 73,4% pada anak kelompok usia 10-14 tahun dan menempati peringkat ke-22 provinsi di Indonesia. Status gizi, kebersihan rongga mulut, pola makan merupakan faktor-faktor yang dapat menyebabkan karies gigi pada anak. Beberapa penelitian melaporkan terdapat hubungan antara status gizi dengan karies gigi. Penelitian ini bertujuan untuk menggambarkan dan menganalisis hubungan status gizi dengan terjadinya karies gigi pada anak usia sekolah dasar di SD Negeri Wonosaren. Metode: Penelitian ini adalah studi penelitian analitik observasional dengan pendekatan cross-sectional. Penelitian ini dilaksanakan pada bulan Agustus-September 2023. Sampel dipilih secara stratified random sampling sebanyak 100 subjek penelitian. Status gizi diukur dengan teknik antropometri, yaitu menggunakan pengukuran tinggi dan berat badan. Pemeriksaan karies gigi dilakukan dengan cara melakukan inspeksi dan sondasi gigi. Data dianalisis dengan menggunakan Statistical Program for Social Science (SPSS) versi 25. Untuk mengetahui hubungan status gizi dengan terjadinya karies gigi dianalisis dengan uji korelasi pearson. Hasil dinyatakan signifikan apabila p<0.05. Hasil: Uji korelasi pearson menunjukkan tidak ada hubungan antara status gizi (IMT/U) dengan karies gigi (p=0.179). Simpulan: Tidak terdapat hubungan antara status gizi dengan terjadinya karies gigi pada anak usia sekolah dasar di SD Negeri Wonosaren. Introduction: Dental and oral health problems in Central Java province are still high, namely 73.4% of children aged 10-14 years, and are ranked 22nd province in Indonesia. Nutritional status, oral hygiene, and diet can cause dental caries in children. Several studies report a relationship between nutritional status and dental caries. This study aims to describe and analyze the relationship between nutritional status and the occurrence of dental caries in elementary school-aged children at Wonosaren State Elementary School. Method: This research is an observational analytical study with a cross-sectional approach. This research was carried out in August-September 2023. The sample was selected using stratified random sampling of 100 research subjects. Nutritional status was measured using the BMI/Age technique, obtained from anthropometric weight and height measurements. Weight is measured using a step scale, and height is measured using a microtome. A dental caries examination is carried out by inspection and dental condition. Data were analyzed using the Statistical Program for Social Science (SPSS) version 25. It was analyzed using the Pearson correlation test to determine the relationship between nutritional status and the occurrence of dental caries. Results are declared significant if p<0.05. Results: Pearson correlation test showed no relationship between nutritional status (BMI/U) and dental caries (p=0.179). Conclusion: There is no relationship between nutritional status and the occurrence of dental caries in elementary school-aged children at SD Negeri Wonosaren.

Latihan fisik teratur memiliki efek positif dalam meningkatkan kapasitas aerobik pada siswa militer. Kusuma, Pranata Aji; Riyadi, Slamet; Handayani, Selfi
Jurnal SPORTIF : Jurnal Penelitian Pembelajaran Vol 11 No 1 (2025): Jurnal SPORTIF: Jurnal Penelitian Pembelajaran
Publisher : Universitas Nusantara PGRI Kediri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29407/js_unpgri.v11i1.23935

Military preparation requires aerobic capacity (VO2max) and physical condition. Studies show that Indonesian Air Force personnel are overweight (34.9%) and obese (9.1%), which may impede task performance. This study examines how stair ascending and descending improve aerobic capacity (VO2 max) in Skadron Pendidikan 404 (Skadik 404) cadets, with BMI as a supportive factor. A quasi-experimental study included 40 cadets aged 19-22 with a BMI of 18.5-24.9 kg/m², divided into four groups: POK 1 (stair climbing), POK 2 (stair descending), POK 3 (stair climbing), and POK 4 (stair descending). This study uses 'POK' to refer to each study group. Data was collected using the 12-minute Cooper Test to measure VO2max. The data was analyzed using pairwise t-tests and two-way ANOVA with 5% significance. The study found significant differences in aerobic capacity (p < 0.05), with the stair-climbing group achieving larger VO₂max improvements than the descending group. These results show that army students may benefit more from stair climbing for aerobic training. This study supports military fitness studies by showing that stair climbing is better than stair descending and suggesting time-efficient, high-intensity training routines to improve soldiers' physical readiness.

INVIVO STUDY OF AQUEOUS EXTRACT OF SNAKE FRUIT SEEDS IN FEMALE RATS WITH ANEMIA Fara Ayu Febyawati, Hani; Indarto, Dono; Handayani, Selfi
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 8, No 4: Desember 2023
Publisher : Universitas Aisyah Pringsewu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30604/jika.v8i4.2533

Anemia remains a global nutritional problem in children, pregnant women and female adolescents because of increasing its prevalence. This study aimed to analyze the effects of aqueoes extract of snake fruit seed (AES) on body weight (BW), body length (BL), body fat percentage (BFP), and wet organ weight in female rats with anemia. This animal experiment used the pre-posttest control group design. A total of 30 female wistar rats with anemia were randomly divided into 5 groups: the negative and positive control groups were given a low iron diet with or without administration of 3.7 mg/200gBW iron supplements, and the treatment (AES1-3) groups were given a low iron diet+AES administration (25,50, and 100 mg/200gBW respectively) for 28 days. Data were analyzed using SPSS 26.0, and STATA MP 17. The average of BW, wet liver and kidney weights in the AES2 group significantly increased, compared to other rat groups. The average of BFP in the AES2 group significantly decreased, compared to the control groups. The average of BL and wet spleen weight did not differ among rat groups. In conclusion, administration of 50 mg/200gBW AES increases BW, wet organ weights, and decreases BFP, but has no effect on BL.

Co-Authors . Balgis . Muthmainah . Muthmainah Achmad Fauzi Kamal Agus Sugeng Riyanto Agustina Wulandari Ahmad Aulia Ahmad Isnaini Shidqi Nurhani Anik Lestari Annisa Aghnia Rahma Annisa Budiastuti Arif Setyoko Arpin, Wilson Aryoseto, Lukman Asyiraq, Muhammad Ferdy Balgis . Balgis Balgis Betty Saptiwi Betty Saptiwi Budiono, Enrico Ananda Budiyanti, Novita Danus Hermawan Dhoni Akbar Ghozali Diniyati, Hilda Dono Indarto Dwi rahayu Dyah Ratna Budiani Dyonisa Nasirochmi Pakha Endang Listyaningsih Endang listyaningsih Endang Listyaningsih Enrico Ananda Budiono Fara Ayu Febyawati, Hani Firnadi, Jossefa Gozali, Dhoni Akbar Hakim, Fikar Arsyad Handayani Putri Cahyaningrum Harahap, Aletta Khaerunnisa Putri Harahap, Alida Roswita Hardjono . Hasan Mihardja Hastami, Yunia Hermawan, Danus Hernowo Setyo Utomo Ida Nurwati Ilyas, Muhana Fawwazy Itsna Ulin Nuha Jarot Subandono Jarot Subandono Kiyatno . kusnandar kusnandar Kusuma, Pranata Aji Luh Karunia Wahyuni, Luh Karunia Lukman Aryoseto M Abdul Basith Maria Mumtaz Martini Martini Mayangsarie, Adhiestya Muhammad Afif Muhammad Luthfiyanto Muhammad Syauqi Ridhallah Muhana Fawwazy Ilyas Muthmainah Muthmainah Muthmainah Muthmainah Nanang Wiyono Nanang Wiyono Nareswari, Irma Nisa'u Luthfi Nur Azizah Nur Dwi Fajarini Nurhani, Ahmad Isnaini Shidqi Nurwijayanti Paksi Suryo Bawono Raditya Perdana Aryasatya Rahma, Annisa Aghnia Rahmawati, Anindita Reflioni, Silvi Retno Asti Werdhani Reyhan Eddy Yunus Ridhallah, Muhammad Syauqi Risya Cilmiaty Risya Cilmiaty A. R. Riyanto, Agus Sugeng Rosyadah, Prima Aprilia Rukmindar, Dion Sarsono Sarsono Shabrina, Syania Siti Marufah Siti Munawaroh Siti Munawaroh slamet Riyadi Slamet Riyadi Sri Haryati Sunggoro, Agus Jati Susanti, Widia Syania Shabrina Widia Susanti Yundari, Yundari

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