Jurnal Indah Sains dan Klinis
Vol 5 No 3 (2024): Jurnal Indah Sains dan Klinis

Potensi Antihiperglikemia Kombinasi Ekstrak Daun Salam dan Ikan Gabus

Razoki, Razoki (Unknown)
Simanjuntak, Nerly Juli Pranita (Unknown)



Article Info

Publish Date
31 Dec 2024

Abstract

Background: Flavonoids, as secondary metabolites found in bay leaves, exhibit antioxidant properties that help prevent damage to pancreatic β cells by neutralizing free radicals responsible for cell injury. Protein from snakehead fish plays a role in regulating blood sugar levels by inhibiting the α-glucosidase enzyme. Objective: This study aimed to assess the potential of combining the two extracts to lower blood sugar levels in mice. Method: Six groups were used in the study, each receiving a 250 mg/kg BW dose and 40% glucose inducer: Aquades (A), ethanol extract of bay leaves (EEDS), snakehead fish extract (EIG), and combinations of ethanol extracts of bay leaves and snakehead fish (EEDS-IG) in ratios of 1:1, 2:1, and 3:1 (w/w). Results: The study revealed that EEDS and EIG reduced blood sugar levels by 12.14%, 66.9%, 55.0%, 69.3%, 69.7%, and 69.3% at the 120th minute, respectively, for each group. Conclusion: The combination of EEDS and EIG has the potential to reduce blood sugar levels, particularly at a 2:1 ratio

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Journal Info

Abbrev

jisk

Publisher

Subject

Dentistry Health Professions Medicine & Pharmacology Nursing

Description

The Jurnal Indah Sains dan Klinis (JISK) is a journal about health which contains scientific and clinical issues published by the Yayasan Penelitian dan Inovasi Sumatera (YPIS) which includes studies on Pharmacy, Medicine, Nursing, Midwifery, Chemistry, Biology, Microbiology, Tissue Culture and ...