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All Journal Jurnal Indah Sains dan Klinis
Razoki Razoki
Fakultas Kedokteran, Kedokteran Gigi dan Ilmu Kesehatan Universitas Prima Indonesia
Dentistry Health Professions Medicine & Pharmacology Nursing

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Potensi Antihiperglikemia Kombinasi Ekstrak Daun Salam dan Ikan Gabus Razoki Razoki; Nerly Juli Pranita Simanjuntak
Jurnal Indah Sains dan Klinis Vol 5 No 3 (2024): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v5i3.04

Abstract

Background: Flavonoids, as secondary metabolites found in bay leaves, exhibit antioxidant properties that help prevent damage to pancreatic β cells by neutralizing free radicals responsible for cell injury. Protein from snakehead fish plays a role in regulating blood sugar levels by inhibiting the α-glucosidase enzyme. Objective: This study aimed to assess the potential of combining the two extracts to lower blood sugar levels in mice. Method: Six groups were used in the study, each receiving a 250 mg/kg BW dose and 40% glucose inducer: Aquades (A), ethanol extract of bay leaves (EEDS), snakehead fish extract (EIG), and combinations of ethanol extracts of bay leaves and snakehead fish (EEDS-IG) in ratios of 1:1, 2:1, and 3:1 (w/w). Results: The study revealed that EEDS and EIG reduced blood sugar levels by 12.14%, 66.9%, 55.0%, 69.3%, 69.7%, and 69.3% at the 120th minute, respectively, for each group. Conclusion: The combination of EEDS and EIG has the potential to reduce blood sugar levels, particularly at a 2:1 ratio
Gambaran Penggunaan Obat Antibiotik dan Analgetik pada Resep Pasien Poli Gigi di RSUD Muyang Kute Razoki Razoki; Elvi Sasmi; Astriani Natalia Br Ginting
Jurnal Indah Sains dan Klinis Vol 6 No 2 (2025): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v6i2.02

Abstract

Background: Dental and oral diseases often lead to infections and pain, thus requiring treatment with antibiotics and analgesics. These conditions, if not treated properly, can significantly impact patients' quality of life and may result in further complications. Objective: This study aims to provide an overview of the use of antibiotics and analgesics in prescriptions for dental clinic patients at RSUD Muyang Kute. Method: A descriptive retrospective study was conducted on 80 prescriptions from patients at the Dental Clinic in September 2024. The sampling technique used was random sampling. Results: The majority of patients were female (60%) and within the age range of 26–45 years (37.5%). The most frequently prescribed antibiotic was amoxicillin (92.5%), followed by a combination of amoxicillin and metronidazole (3.75%), lincomycin (2.5%), and cefadroxil (1.25%). The most commonly used analgesic was a combination of paracetamol and dexamethasone (97.5%), followed by mefenamic acid and dexamethasone (2.5%). Conclusion: Amoxicillin and the combination of paracetamol-dexamethasone were the preferred drugs due to their high effectiveness, safety, and relatively affordable cost.
Profil Pelayanan Resep dengan Obat Glibenklamid di Apotek Wilayah Nagan Raya Razoki Razoki; Friska Rezki Hasibuan
Jurnal Indah Sains dan Klinis Vol 6 No 2 (2025): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v6i2.04

Abstract

Background: Community pharmacies have shifted from focusing only on products to providing care centered on patients. Pharmacists now have the role of gathering patient information, giving proper counseling, and ensuring medicine labels are clear and correct. This is crucial for chronic diseases like type 2 diabetes mellitus, where drugs such as glibenclamide must be used properly to avoid risks. Objective: This study aimed to describe how pharmacies in Nagan Raya provide prescription services for glibenclamide, especially in terms of patient data collection, counseling, and labeling. Methods: A descriptive study was done using the simulated patient method. A total of 90 pharmacies were randomly chosen. The researcher acted as a patient’s family member and presented a prescription for glibenclamide. Observations were recorded right after each visit using a structured and validated checklist. Results: Of the 90 pharmacies visited, 85 (94.4%) dispensed the medicine. However, only 18.8% asked for the patient's address, and fewer than 10% asked about other key information like user identity or medication history. No pharmacy asked about symptoms, allergies, or comorbidities. For counseling, 64.7% mentioned how often to take the drug, 15.3% explained timing, and just 1.2% discussed side effects. Labels were provided in 65.9% of cases, but some were incomplete or used wrongly. Conclusion: The quality of prescription services for glibenclamide in Nagan Raya is still lacking. Important steps like patient assessment and counseling are often missed. Better training and stronger supervision are needed to improve pharmacy services and ensure patient safety
Profil Pelayanan Resep dengan Obat Glibenklamid di RSUD Muyang kute Bener Meriah Masriani; Razoki Razoki; Astriani Natalia Br Ginting
Jurnal Indah Sains dan Klinis Vol 6 No 2 (2025): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v6i2.03

Abstract

Background: Optimal pharmaceutical services are essential in chronic disease management, particularly in diabetes mellitus, where glibenclamide is frequently prescribed. Inadequate dispensing practices and lack of patient information can compromise treatment outcomes. Objective: This study aimed to evaluate the profile of prescription services involving glibenclamide at RSUD Muyang Kute Bener Meriah, focusing on drug availability, patient information gathering, medication counseling, and labeling practices. Methods: A descriptive observational design was applied using the simulated patient method. Researchers visited the pharmacy unit with a standardized prescription scenario involving glibenclamide. Data were collected using an observation checklist immediately after each interaction. Results:The majority of pharmacy staff did not actively collect essential patient information. Counseling was limited to usage instructions, with no mention of adverse effects or drug interactions. Labels were incomplete, often missing key components such as patient name, drug name, or preparation date. However, the availability of glibenclamide remained consistent during the observation period. Conclusion: Prescription services for glibenclamide at RSUD Muyang Kute are still below optimal standards. Improvements in patient assessment, communication, and labeling practices are necessary to enhance medication safety and treatment effectiveness
Co-Authors Elvi Sasmi Friska Rezki Hasibuan Ginting, Astriani Natalia Br Masriani Nerly Juli Pranita Simanjuntak