Jurnal Farmasi dan Sains Indonesia (JFSI)
Vol 7 No 2 (2024)

Aktivitas Daya Ingat Ekstrak Daun Pecut Kuda (Stachtarpheta jamaicensis L. (Vahl) Pada Mencit Putih (Mus musculus) Dengan Metode Radial Arm Maze

Septiarini, Anita Dwi (Unknown)
Pratama, Kharisma Jayak (Unknown)
Andhika, Intan Fatna (Unknown)



Article Info

Publish Date
28 Dec 2024

Abstract

Alzheimer's disease is the most common type of dementia. Horse whip leaves contain flavonoid compounds which are widely used both in physiological aging studies and in rat model research, to research the cure of neurodegenerative diseases. The purpose of this study was to determine the activity of giving horse whip leaf extract and the effective dose of horse whip leaf extract in improving the memory power of mice. Horse whip leaf extract was extracted using 96% ethanol solvent by maceration method. Memory activity testing was carried out on male mice which were divided into 5 groups, namely the negative control group, the positive control group, the horse whip leaf extract test group at doses of 5, 10 and 20 mg/kg BW. The test was carried out using the radial arm maze method. The results showed that horse whip leaf extract had memory enhancing activity. Test animals that have been induced given treatment are known to experience a decrease in latency time which can be stated as test animals experience an increase in memory activity. The effective extract dose was a dose of 20 mg/kgBW with a difference in latency time of 49.80 second.

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Journal Info

Abbrev

jfsi

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Medicine & Pharmacology Neuroscience

Description

Focus and Scope Jurnal Farmasi & Sains Indonesia is an open-access journal that published twice a year by Sekolah Tinggi Ilmu Farmasi Nusaputera. This journal is a media of research publication on all aspects of pharmaceutical & science that is innovative, creative, original and based on scientific. ...