Sinteza
Vol. 5 No. 1 (2025): February

Pengaruh Konsentrasi Karbopol sebagai Emulgator terhadap Karakteristik Fisik Sediaan Lotion Ekstrak Daun Belimbing Wuluh (Averrhoa bilimbi L.)

Palma, Retno Dela (Unknown)
Devi, Sisca (Unknown)



Article Info

Publish Date
15 Feb 2025

Abstract

Starfruit leaf extract produces antioxidant activity from the flavonoid compound content. The lotion dosage form is one of the dosage forms used as an antioxidant application to the skin. The lotion formula consists of a water phase, an oil phase, and an emulsifier. The emulsifier is the most important part of the formation of lotion because it determines the physical characteristics produced and the stability of the preparation. Carbopol is a synthetic emulsifier that can absorb liquid and form a stable mass to produce stable physical characteristics of the lotion. The purpose of this study was to influence the concentration of carbopol on the physical attributes of starfruit leaf extract lotion and to determine the concentration of carbopol with the best physical characteristics of starfruit leaf extract lotion. This study is an experimental study with different concentrations of Carbopol, namely 0.3%; 0.4%; and 0.5%. The physical characteristics measured were organoleptic, pH, homogeneity, viscosity, spreadability, adhesion, protection power, and emulsion type. Viscosity and adhesion test data were tested using Kruskal Wallis and continued with Mann Whitney, while spreadability and protection test data were tested using ANOVA followed by Pos Hoc. The results showed that increasing the concentration of Carbopol affected protection power (p<0.05). The concentration of Carbopol that produced the best characteristics was 0.3% (formula 1).

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Journal Info

Abbrev

sinteza

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology

Description

Sinteza, ISSN (online) 2797-8133, is a peer-reviewed journal in pharmacy. Established 2021, the journal is an open access of published articles to support greater exposure of scientific knowledge. Sinteza published online twice a year by Faculty of Health, Universitas hamzanwadi. Sinteza accepts ...