The Effect of Personal Protective Equipment Uptake on the Risk of Leprosy in Adults: Meta Analysis

Saputra, Rizki Kurniawan
Rahardjo, Setyo Sri
Murti, Bhisma

Journal of Health Promotion and Behavior
Vol. 6 No. 1 (2021)

Background: Leptospirosis is an acute infec­tious disease that can attack humans and ani­mals caused by the Leptospira bacteria. Lepto­spirosis contributes to morbidity and mortality in the high-risk group, namely adults. Compli­ance with the use of personal protective equip­ment and direct contact with animal tissue infected with Leptospira sp. bacteria increase the risk of leptospirosis. This study aims to ana­lyze the magnitude of the effect of using per­sonal protective equipment on the risk of leptospirosis with a meta-analysis.Subjects and Method: This was a systematic review and meta-analysis carried out by follow­ing the PRISMA flow diagram. The process of searching for articles is through a journal data­base which includes: PubMed, Springer Link, Google Scholar and Science Direct by selecting articles published in 1999-2020. Keywords used "Leptospirosis AND Personal Protective Equipment", "leptospirosis" AND "risk factors", "leptospirosis AND adjusted odds ratio", "lepto­spirosis" AND "adults", "leptospirosis AND risk factors AND adjusted odds ratio". The inclu­sion criteria were full paper articles with observa­tio­nal study design, articles in English and Indo­nesian, multivariate analysis used with adjusted odds ratio. Articles that meet the requirements are analyzed using the Revmen 5.3 application.Results: A total of 8 articles were reviewed in this study with a cross-sectional and case-control study design. Meta-analysis of 4 case-control studies showed that non-adherence to the use of personal protective equipment had a 2.77 times increased risk of leptospirosis compared with using personal protective equipment (aOR= 2.77, 95% CI= 1.76 to 4.36, p <0.001). A meta-analysis of 4 cross-sectional studies concluded that non-adherence to the use of personal protective equip­ment had a 2.73 times increased risk of lepto­spirosis compared with using personal protective equipment (aOR= 2.73, 95% CI= 1.99 to 3.74; p= <0.001).Conclusion: Non-compliance with the use of personal protective equipment increases the risk of leptospirosis.Keywords: leptospirosis, personal protective equipment, meta-analysisCorrespondence: Rizki Kurniawan Saputra. Masters Program in Public Health, Universitas Sebelas Maret. Jl.Ir. Sutami 36A, Surakarta 57126, Central Java. Email: [e-mail]. Mobile: [phone].Journal of Health Promotion and Behavior (2021), 06(01): 21-3https://doi.org/10.26911/thejhpb.2021.06.01.03