Makassar Natural Product Journal
Juli 2024

INHIBISI ENZIM α-GLUKOSIDASE PADA SENYAWA TECTOQUINONE YANG DIISOLASI DARI Syzygium oblanceolatum (C.B.ROB.) MERR

Najib, Ahmad (Unknown)



Article Info

Publish Date
19 Aug 2024

Abstract

Syzygium oblanceolatum (C.B.Rob.) Merr. Has several medicinal benefits, empirically its leaf decoction has been used as an antidiabetic. Several representatives of the Syzygium genus have been proposed to possess chemical compounds, nutraceutical values, and biological activities. In particular, previous studies have emphasized the abundance of bioactive chemicals, including flavonoids, phenolic acids, triterpenoids, and volatile compounds. Several representatives of the genus Syzygium have been proposed to possess chemical compounds, nutraceutical values, and biological activities. In particular, previous studies have emphasized the abundance of bioactive chemicals, including flavonoids, phenolic acids, triterpenoids, and volatile compounds. The tectoquinone compound isolated from Syzygium oblanceolatum (C.B. Rob.) Merr based on its chemical structure is a substituted anthraquinone, namely 2-methylanthraquinone. This study aims to determine the Tectoquinone compound as an α-glucosidase inhibitor and determine the IC50 value of the tectoquinone compound. The method of this research was an α-glucosidase inhibition test using ELISA reader instrument by measuring the absorbance at the maximum wavelength of 405 nm using an acarbose comparator. The results of the α-glucosidase inhibition test of the akarbosa comparator had an IC50 value of 0.258 μg/mL and the IC50 value of the tectoquinone compound was 155.184 μg/mL.

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Journal Info

Abbrev

mnpj

Publisher

Subject

Medicine & Pharmacology

Description

Makassar Natural Product Journal merupakan salah satu jurnal yang dikelola oleh Fakultas Farmasi Universitas Muslim Indonesia yang terbit pertama kali pada bulan Maret 2023. Makassar Natural Product Journal merupakan jurnal ilmiah yang terbit secara on-line dan menerbitkan artikel atau karya ilmiah ...