Jurnal Konseling dan Pendidikan
Vol. 13 No. 1 (2025): JKP

Procons omega-3: the key to fighting inflammation and preventing muscle loss in sarcopenic patients

Tjakradidjaja, Francisca A (Unknown)



Article Info

Publish Date
27 Mar 2025

Abstract

Sarcopenia, an age-related progressive loss of muscle mass and function, is a significant public health concern that increases the risk of frailty, falls, and disability among older adults. Inflammation plays a crucial role in accelerating muscle degradation, making anti-inflammatory interventions essential in managing sarcopenia. This study employs a qualitative approach through literature review and library research to explore the potential of omega-3 fatty acids as a therapeutic strategy for preventing muscle loss and mitigating inflammation in sarcopenic patients. Omega-3 polyunsaturated fatty acids (PUFAs), particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), exhibit potent anti-inflammatory properties that regulate cytokine production and muscle protein synthesis pathways. Existing studies indicate that omega-3 supplementation can enhance muscle protein anabolism, reduce systemic inflammation, and improve physical function in older adults at risk of sarcopenia. Moreover, omega-3 fatty acids modulate key inflammatory markers such as tumor necrosis factor-alpha (TNF-α) and interleukin-6 (IL-6), which are linked to muscle degradation. Through an in-depth analysis of scientific literature, this study highlights the potential benefits of omega-3 supplementation as a non-pharmacological intervention for sarcopenia. However, further clinical trials are needed to determine the optimal dosage, duration, and long-term effects of omega-3 on muscle preservation. The findings of this study contribute to the growing body of research advocating for dietary interventions as a preventive strategy against age-related muscle loss and chronic inflammation.

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Journal Info

Abbrev

jkp

Publisher

Subject

Education

Description

Jurnal Konseling dan Pendidikan merupakan jurnal ilmiah dalam bidang keilmuan Bimbingan dan Konseling dan Pendidikan. Jurnal ini diterbitkan oleh Indonesian Institute for Counseling And Education (IICE), merupakan sub lembaga dari perusahaan Multikarya Kons merupakan salah satu Pusat Kajian, Latihan ...